LINC00575

Summary

LINC00575 (long intergenic non-protein coding RNA 575, HGNC:21342) is a long non-coding RNA gene on chromosome 4q21.22.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:21342
Approved symbol	LINC00575
Name	long intergenic non-protein coding RNA 575
Location	4q21.22
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000231782
Ensembl biotype	lncRNA
Entrez	439934
RNAcentral	URS0000556605 — lncRNA, 910 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 3 — 3 lncRNA

ENST00000426551, ENST00000515811, ENST00000651054

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000426551 — 4 exons

Exon	Start	End
ENSE00001629035	82614893	82615081
ENSE00001738468	82613113	82613384
ENSE00001740628	82621212	82621437
ENSE00001760094	82613872	82614094

Expression profiles

Bgee: expression breadth broad, 90 present calls, max score 73.16.

Top tissues by expression

90 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sural nerve	UBERON:0015488	73.16	gold quality
corpus callosum	UBERON:0002336	63.93	gold quality
endometrium	UBERON:0001295	55.03	gold quality
placenta	UBERON:0001987	53.44	silver quality
calcaneal tendon	UBERON:0003701	53.05	silver quality
monocyte	CL:0000576	52.81	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	52.33	silver quality
blood	UBERON:0000178	51.80	silver quality
liver	UBERON:0002107	51.22	silver quality
duodenum	UBERON:0002114	50.62	gold quality
islet of Langerhans	UBERON:0000006	49.48	gold quality
right lobe of thyroid gland	UBERON:0001119	49.06	gold quality
bone marrow	UBERON:0002371	48.48	silver quality
vermiform appendix	UBERON:0001154	47.36	gold quality
superior frontal gyrus	UBERON:0002661	47.28	silver quality
prefrontal cortex	UBERON:0000451	47.14	silver quality
muscle of leg	UBERON:0001383	46.83	silver quality
myometrium	UBERON:0001296	46.51	gold quality
adrenal tissue	UBERON:0018303	46.27	silver quality
heart	UBERON:0000948	45.92	silver quality
gastrocnemius	UBERON:0001388	45.65	silver quality
olfactory segment of nasal mucosa	UBERON:0005386	45.22	silver quality
frontal cortex	UBERON:0001870	44.76	silver quality
kidney	UBERON:0002113	44.58	silver quality
primary visual cortex	UBERON:0002436	44.47	silver quality
adult mammalian kidney	UBERON:0000082	44.18	silver quality
body of pancreas	UBERON:0001150	44.17	silver quality
right hemisphere of cerebellum	UBERON:0014890	44.15	silver quality
heart left ventricle	UBERON:0002084	43.87	silver quality
tonsil	UBERON:0002372	43.82	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	2.62

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• One transcript expressed exclusively in retina and retinal pigment epithelium is the novel gene C4orf11 which is comprised of four exons on chromosome 4q21.2 (PMID:15218245)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.