LINC00581

Summary

LINC00581 (long intergenic non-protein coding RNA 581, HGNC:43840) is a long non-coding RNA gene on chromosome 6p22.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:43840
Approved symbol	LINC00581
Name	long intergenic non-protein coding RNA 581
Location	6p22.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000280989
Ensembl biotype	lncRNA
Entrez	100874531
RNAcentral	URS000075AAC4 — lncRNA, 995 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 20 — 20 lncRNA

ENST00000630914, ENST00000637901, ENST00000652307, ENST00000840107, ENST00000840108, ENST00000840109, ENST00000840110, ENST00000840111, ENST00000840112, ENST00000840113, ENST00000840114, ENST00000840115, ENST00000840116, ENST00000840117, ENST00000840118, ENST00000840119, ENST00000840120, ENST00000840121, ENST00000840122, ENST00000840123

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000630914 — 4 exons

Exon	Start	End
ENSE00003769789	21511536	21511895
ENSE00003772170	21502442	21502511
ENSE00003775129	21486061	21486529
ENSE00003775237	21490208	21490298

Expression profiles

Bgee: expression breadth broad, 95 present calls, max score 76.03.

Top tissues by expression

95 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	76.03	silver quality
hindlimb stylopod muscle	UBERON:0004252	64.05	gold quality
sural nerve	UBERON:0015488	63.89	silver quality
ganglionic eminence	UBERON:0004023	62.03	gold quality
cortical plate	UBERON:0005343	60.50	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	58.76	gold quality
prefrontal cortex	UBERON:0000451	53.85	gold quality
monocyte	CL:0000576	53.16	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	52.41	gold quality
calcaneal tendon	UBERON:0003701	51.60	silver quality
liver	UBERON:0002107	51.05	silver quality
bone marrow	UBERON:0002371	50.87	silver quality
islet of Langerhans	UBERON:0000006	50.35	gold quality
blood	UBERON:0000178	50.35	silver quality
gall bladder	UBERON:0002110	49.76	gold quality
placenta	UBERON:0001987	49.75	gold quality
small intestine	UBERON:0002108	48.96	silver quality
nucleus accumbens	UBERON:0001882	48.72	gold quality
duodenum	UBERON:0002114	48.49	silver quality
putamen	UBERON:0001874	48.19	gold quality
hypothalamus	UBERON:0001898	48.04	gold quality
pancreas	UBERON:0001264	47.80	gold quality
superior frontal gyrus	UBERON:0002661	47.38	silver quality
testis	UBERON:0000473	47.23	gold quality
pituitary gland	UBERON:0000007	47.21	gold quality
muscle of leg	UBERON:0001383	46.85	silver quality
frontal cortex	UBERON:0001870	46.81	gold quality
caudate nucleus	UBERON:0001873	46.28	gold quality
endometrium	UBERON:0001295	45.72	gold quality
body of pancreas	UBERON:0001150	45.57	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.29

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.