LINC00588

Summary

LINC00588 (long intergenic non-protein coding RNA 588, HGNC:24494) is a long non-coding RNA gene on chromosome 8q12.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:24494
Approved symbol	LINC00588
Name	long intergenic non-protein coding RNA 588
Location	8q12.1
Locus type	RNA, long non-coding
Status	Approved
Aliases	DKFZP434F122
Ensembl gene	ENSG00000215117
Ensembl biotype	lncRNA
Entrez	26138
RNAcentral	URS000075D76D — lncRNA, 1879 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000521663, ENST00000838271, ENST00000838272, ENST00000838273

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000521663 — 4 exons

Exon	Start	End
ENSE00001686865	57281971	57282214
ENSE00001731174	57284161	57284275
ENSE00002130645	57284438	57286968
ENSE00002132604	57279543	57280764

Expression profiles

Bgee: expression breadth broad, 26 present calls, max score 71.46.

Top tissues by expression

26 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	71.46	silver quality
cortex of kidney	UBERON:0001225	68.94	gold quality
testis	UBERON:0000473	49.43	gold quality
left testis	UBERON:0004533	49.35	gold quality
prefrontal cortex	UBERON:0000451	48.52	silver quality
hindlimb stylopod muscle	UBERON:0004252	48.07	silver quality
right testis	UBERON:0004534	47.98	gold quality
muscle of leg	UBERON:0001383	47.24	gold quality
kidney	UBERON:0002113	46.99	gold quality
gastrocnemius	UBERON:0001388	45.95	gold quality
amygdala	UBERON:0001876	44.09	gold quality
substantia nigra	UBERON:0002038	42.70	gold quality
prostate gland	UBERON:0002367	42.57	silver quality
dorsolateral prefrontal cortex	UBERON:0009834	41.94	gold quality
Brodmann (1909) area 9	UBERON:0013540	41.13	silver quality
hypothalamus	UBERON:0001898	41.06	gold quality
subcutaneous adipose tissue	UBERON:0002190	40.95	silver quality
Ammon’s horn	UBERON:0001954	40.77	gold quality
blood	UBERON:0000178	40.71	silver quality
putamen	UBERON:0001874	39.98	silver quality
adult mammalian kidney	UBERON:0000082	39.21	silver quality
anterior cingulate cortex	UBERON:0009835	38.97	silver quality
caudate nucleus	UBERON:0001873	38.60	silver quality
right frontal lobe	UBERON:0002810	37.91	silver quality
nucleus accumbens	UBERON:0001882	37.22	silver quality
C1 segment of cervical spinal cord	UBERON:0006469	35.82	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.