LINC00595

Summary

LINC00595 (long intergenic non-protein coding RNA 595, HGNC:31430) is a long non-coding RNA gene on chromosome 10q22.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:31430
Approved symbol	LINC00595
Name	long intergenic non-protein coding RNA 595
Location	10q22.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000230417
Ensembl biotype	lncRNA
Entrez	414243
RNAcentral	URS0000D78019 — lncRNA, 860 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 51 — 51 lncRNA

ENST00000415959, ENST00000421324, ENST00000423770, ENST00000432742, ENST00000434974, ENST00000459633, ENST00000461034, ENST00000476909, ENST00000510550, ENST00000624665, ENST00000634389, ENST00000634452, ENST00000634735, ENST00000634930, ENST00000634933, ENST00000634946, ENST00000635180, ENST00000635422, ENST00000635520, ENST00000635545, ENST00000653428, ENST00000659477, ENST00000659842, ENST00000665488, ENST00000667413, ENST00000668124, ENST00000670962, ENST00000764681, ENST00000780307, ENST00000780308, ENST00000780309, ENST00000780310, ENST00000780311, ENST00000780312, ENST00000780313, ENST00000780314, ENST00000813723, ENST00000813724, ENST00000813725, ENST00000813726, ENST00000813727, ENST00000813728, ENST00000813729, ENST00000813730, ENST00000813731, ENST00000813732, ENST00000813733, ENST00000813734, ENST00000813735, ENST00000813736, ENST00000813737

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000415959 — 3 exons

Exon	Start	End
ENSE00001601919	78270034	78270109
ENSE00001633862	78267328	78267486
ENSE00001692509	78277917	78278065

Expression profiles

Bgee: expression breadth ubiquitous, 155 present calls, max score 80.46.

FANTOM5 (CAGE): breadth broad, TPM avg 1.0485 / max 57.4145, expressed in 328 samples.

FANTOM5 promoters (5 alternative TSS)

Promoter ID	TPM avg	Samples expressed
105679	0.5848	196
105677	0.3011	85
105683	0.0863	37
105682	0.0688	33
105686	0.0075	4

Top tissues by expression

237 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
ganglionic eminence	UBERON:0004023	80.46	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	79.82	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	78.99	gold quality
ventricular zone	UBERON:0003053	78.18	gold quality
anterior cingulate cortex	UBERON:0009835	77.82	gold quality
putamen	UBERON:0001874	76.32	gold quality
prefrontal cortex	UBERON:0000451	75.50	gold quality
right frontal lobe	UBERON:0002810	75.05	gold quality
amygdala	UBERON:0001876	75.04	gold quality
nucleus accumbens	UBERON:0001882	75.01	gold quality
hypothalamus	UBERON:0001898	74.70	gold quality
caudate nucleus	UBERON:0001873	74.29	gold quality
Brodmann (1909) area 9	UBERON:0013540	73.87	gold quality
muscle layer of sigmoid colon	UBERON:0035805	72.82	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	72.74	gold quality
ileal mucosa	UBERON:0000331	71.53	silver quality
upper arm skin	UBERON:0004263	71.22	gold quality
neocortex	UBERON:0001950	71.04	gold quality
substantia nigra	UBERON:0002038	70.94	gold quality
spinal cord	UBERON:0002240	70.92	gold quality
bone marrow cell	CL:0002092	70.69	silver quality
dorsolateral prefrontal cortex	UBERON:0009834	70.20	gold quality
frontal cortex	UBERON:0001870	69.74	gold quality
midbrain	UBERON:0001891	68.83	gold quality
corpus callosum	UBERON:0002336	68.64	gold quality
colonic epithelium	UBERON:0000397	68.59	silver quality
pancreatic ductal cell	CL:0002079	68.52	silver quality
forebrain	UBERON:0001890	68.50	gold quality
cortical plate	UBERON:0005343	68.21	gold quality
cerebral cortex	UBERON:0000956	67.67	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	5.18

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.