LINC00601

Summary

LINC00601 (long intergenic non-protein coding RNA 601, HGNC:43916) is a long non-coding RNA gene on chromosome 10q26.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:43916
Approved symbol	LINC00601
Name	long intergenic non-protein coding RNA 601
Location	10q26.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000235180
Ensembl biotype	lncRNA
Entrez	101101772
RNAcentral	URS0000403047 — lncRNA, 1168 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 10 — 10 lncRNA

ENST00000456514, ENST00000766402, ENST00000766403, ENST00000766404, ENST00000766405, ENST00000766406, ENST00000766407, ENST00000766408, ENST00000766409, ENST00000766410

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000456514 — 4 exons

Exon	Start	End
ENSE00001641370	126416800	126416911
ENSE00001685542	126413869	126414738
ENSE00001692863	126421787	126421879
ENSE00001799229	126417716	126417808

Expression profiles

Bgee: expression breadth broad, 90 present calls, max score 81.78.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.3376 / max 18.0555, expressed in 182 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
111959	0.3376	182

Top tissues by expression

90 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
corpus callosum	UBERON:0002336	81.78	gold quality
sural nerve	UBERON:0015488	71.11	gold quality
calcaneal tendon	UBERON:0003701	63.83	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	63.32	gold quality
ganglionic eminence	UBERON:0004023	60.57	gold quality
tonsil	UBERON:0002372	59.72	silver quality
hindlimb stylopod muscle	UBERON:0004252	57.67	gold quality
substantia nigra	UBERON:0002038	56.92	gold quality
Ammon’s horn	UBERON:0001954	55.06	gold quality
primary visual cortex	UBERON:0002436	54.98	gold quality
putamen	UBERON:0001874	54.88	gold quality
prefrontal cortex	UBERON:0000451	54.50	gold quality
amygdala	UBERON:0001876	54.16	gold quality
caudate nucleus	UBERON:0001873	53.25	gold quality
monocyte	CL:0000576	52.77	silver quality
superior frontal gyrus	UBERON:0002661	52.67	gold quality
stromal cell of endometrium	CL:0002255	52.42	silver quality
frontal cortex	UBERON:0001870	52.00	gold quality
brain	UBERON:0000955	51.74	gold quality
blood	UBERON:0000178	51.51	silver quality
hypothalamus	UBERON:0001898	51.19	gold quality
cerebral cortex	UBERON:0000956	50.98	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	50.67	silver quality
nucleus accumbens	UBERON:0001882	50.55	gold quality
gall bladder	UBERON:0002110	50.41	gold quality
Brodmann (1909) area 9	UBERON:0013540	50.17	gold quality
right frontal lobe	UBERON:0002810	50.05	gold quality
placenta	UBERON:0001987	49.65	gold quality
lung	UBERON:0002048	48.95	gold quality
anterior cingulate cortex	UBERON:0009835	48.91	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.80

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Linc00601 upregulation promotes hepatocellular carcinoma development by activating MAPK signaling pathway. (PMID:32572918)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.