LINC00606

Summary

LINC00606 (long intergenic non-protein coding RNA 606, HGNC:43931) is a long non-coding RNA gene on chromosome 3p25.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:43931
Approved symbol	LINC00606
Name	long intergenic non-protein coding RNA 606
Location	3p25.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000226567
Ensembl biotype	lncRNA
Entrez	285370
RNAcentral	URS0000CCE095 — lncRNA, 3028 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000412578, ENST00000436060, ENST00000664856, ENST00000741253, ENST00000741254, ENST00000741255

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000412578 — 3 exons

Exon	Start	End
ENSE00001629861	10763200	10763497
ENSE00001666472	10759484	10761922
ENSE00001760039	10764061	10764192

Expression profiles

Bgee: expression breadth broad, 34 present calls, max score 69.38.

Top tissues by expression

172 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
buccal mucosa cell	CL:0002336	69.38	gold quality
sural nerve	UBERON:0015488	65.37	gold quality
ganglionic eminence	UBERON:0004023	60.56	gold quality
left testis	UBERON:0004533	59.72	gold quality
right testis	UBERON:0004534	58.87	gold quality
testis	UBERON:0000473	57.67	gold quality
sperm	CL:0000019	56.67	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	52.92	gold quality
prefrontal cortex	UBERON:0000451	48.91	gold quality
upper lobe of lung	UBERON:0008948	46.77	silver quality
lower lobe of lung	UBERON:0008949	46.54	silver quality
tendon of biceps brachii	UBERON:0008188	45.44	gold quality
middle temporal gyrus	UBERON:0002771	45.38	gold quality
skin of abdomen	UBERON:0001416	45.34	gold quality
tibial nerve	UBERON:0001323	43.90	silver quality
gastrocnemius	UBERON:0001388	43.76	gold quality
frontal cortex	UBERON:0001870	43.40	silver quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	43.37	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	43.17	silver quality
Brodmann (1909) area 9	UBERON:0013540	42.98	silver quality
neocortex	UBERON:0001950	42.76	silver quality
anatomical system	UBERON:0000467	42.65	gold quality
secondary oocyte	CL:0000655	42.57	gold quality
material anatomical entity	UBERON:0000465	42.54	gold quality
spinal cord	UBERON:0002240	42.52	silver quality
multicellular organism	UBERON:0000468	42.51	gold quality
tendon	UBERON:0000043	42.36	gold quality
lung	UBERON:0002048	42.16	gold quality
amygdala	UBERON:0001876	41.90	silver quality
cortex of kidney	UBERON:0001225	41.88	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.13

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• LINC00606 promotes glioblastoma progression through sponge miR-486-3p and interaction with ATP11B. (PMID:38725030)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.