LINC00618

Summary

LINC00618 (long intergenic non-protein coding RNA 618, HGNC:20110) is a long non-coding RNA gene on chromosome 14q32.2.

At a glance

• GWAS associations: 2

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:20110
Approved symbol	LINC00618
Name	long intergenic non-protein coding RNA 618
Location	14q32.2
Locus type	RNA, long non-coding
Status	Approved
Entrez	145249
RNAcentral	URS000075C7BF — lncRNA, 361 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 0

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

None — 0 exons

Expression profiles

Top tissues by expression

0 total, by Bgee expression score (0-100, higher = more expressed):

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Protein identifiers

Canonical reviewed UniProt: None (reviewed: )

All UniProt accessions (0):

RefSeq proteins (0): (*=MANE)

Domains & families (InterPro)

Structure

Experimental structures (PDB)

0 structures.

Predicted structure (AlphaFold)

Function

Pathways and Gene Ontology

Reactome pathways

0 pathways

MSigDB gene sets: 0 (showing top):

GO Biological Process (0):

GO Molecular Function (0):

GO Cellular Component (0):

Protein interactions and networks

STRING

0 interactions, top by confidence (×1000):

IntAct

0 interactions, top by confidence:

SIGNOR signaling

0 interactions.

Disease & clinical

Clinical variants and AI predictions

ClinVar

0 variants total. Per-class counts are floors (≥ shown; pagination cap):

Classification	Count (floor)
Pathogenic	0
Likely pathogenic	0
Uncertain significance	0
Likely benign	0
Benign	0

Top pathogenic / likely-pathogenic (0)

SpliceAI

0 predictions. Top by Δscore:

AlphaMissense

0 scored. Top likely-pathogenic:

dbSNP variants (sampled 300 via entrez): RS1000744457 (14:96942685 G>A), RS1001409449 (14:96945275 G>A,C), RS1001530565 (14:96944103 T>C), RS1002538867 (14:96945146 A>T), RS1003166075 (14:96944842 C>A), RS1003249028 (14:96942529 C>G), RS1004770831 (14:96945363 A>G), RS1004955857 (14:96944569 C>T), RS1006415601 (14:96942290 C>G,T), RS1006790521 (14:96942055 G>A), RS1007693298 (14:96941837 A>G), RS1008423294 (14:96944516 G>A), RS1008808924 (14:96944361 T>C), RS1009434300 (14:96943017 G>A), RS1010439709 (14:96944138 T>A)

Disease associations

OMIM: gene `` | disease phenotypes:

GenCC curated gene-disease

Mondo (0):

Orphanet (0):

HPO phenotypes

0 total (0 of 0 shown, HPO-id order):

GWAS associations

2 associations (top):

Study	Trait	p-value
GCST003542_95	Night sleep phenotypes	8.000000e-06
GCST008529_20	Tea consumption	2.000000e-06

EFO canonical traits (1, from GWAS)

EFO ID	Trait name
EFO:0010091	tea consumption measurement

Drugs & pharmacology

Drug and pharmacology data

Is drug target: no

PharmGKB: 1 entry (VIP=true, CPIC=false)

CTD chemical–gene interactions

1 total (human), top 1 by PubMed support.

Chemical	Actions (top 5)	PubMed papers
Triclosan	increases expression	1

Clinical trials (associated diseases)

0 trials via MONDO — disease-level, not drug-specific.