LINC00621

Summary

LINC00621 (long intergenic non-protein coding RNA 621, HGNC:44227) is a long non-coding RNA gene on chromosome 13q12.12.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:44227
Approved symbol	LINC00621
Name	long intergenic non-protein coding RNA 621
Location	13q12.12
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000262619
Ensembl biotype	lncRNA
Entrez	100996930
RNAcentral	URS0000A769F1 — lncRNA, 1168 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 9 — 9 lncRNA

ENST00000577004, ENST00000658532, ENST00000663150, ENST00000668623, ENST00000669934, ENST00000685691, ENST00000744250, ENST00000744251, ENST00000744252

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000577004 — 5 exons

Exon	Start	End
ENSE00002659955	22896361	22896502
ENSE00002683615	22894606	22895038
ENSE00003864551	22872637	22873274
ENSE00003870921	22876298	22876474
ENSE00004083476	22915718	22916466

Expression profiles

Bgee: expression breadth ubiquitous, 126 present calls, max score 77.09.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.3696 / max 16.6348, expressed in 177 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
136402	0.3471	169
136403	0.0225	6

Top tissues by expression

126 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	77.09	gold quality
ventricular zone	UBERON:0003053	70.43	gold quality
endometrium	UBERON:0001295	70.21	gold quality
cortical plate	UBERON:0005343	68.69	gold quality
ganglionic eminence	UBERON:0004023	66.12	gold quality
bone marrow cell	CL:0002092	64.94	silver quality
skeletal muscle tissue	UBERON:0001134	63.59	silver quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	62.96	gold quality
kidney	UBERON:0002113	62.71	gold quality
adult mammalian kidney	UBERON:0000082	61.81	gold quality
superior frontal gyrus	UBERON:0002661	61.48	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	61.18	gold quality
cortex of kidney	UBERON:0001225	61.08	gold quality
primary visual cortex	UBERON:0002436	61.06	gold quality
metanephros cortex	UBERON:0010533	60.96	gold quality
right frontal lobe	UBERON:0002810	60.85	gold quality
anterior cingulate cortex	UBERON:0009835	60.83	gold quality
endocervix	UBERON:0000458	60.63	gold quality
cerebral cortex	UBERON:0000956	59.22	gold quality
Brodmann (1909) area 9	UBERON:0013540	59.20	gold quality
frontal cortex	UBERON:0001870	58.54	gold quality
liver	UBERON:0002107	58.53	gold quality
hindlimb stylopod muscle	UBERON:0004252	57.91	gold quality
blood	UBERON:0000178	57.50	gold quality
temporal lobe	UBERON:0001871	56.83	gold quality
amygdala	UBERON:0001876	56.71	gold quality
right uterine tube	UBERON:0001302	56.35	gold quality
prefrontal cortex	UBERON:0000451	55.84	gold quality
brain	UBERON:0000955	55.61	gold quality
tonsil	UBERON:0002372	55.41	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.62

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.