LINC00636

Summary

LINC00636 (long intergenic non-protein coding RNA 636, HGNC:27702) is a long non-coding RNA gene on chromosome 3q13.12.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:27702
Approved symbol	LINC00636
Name	long intergenic non-protein coding RNA 636
Location	3q13.12
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000240423
Ensembl biotype	lncRNA
Entrez	285205
RNAcentral	URS000075C324 — lncRNA, 1361 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 8 — 8 lncRNA

ENST00000494231, ENST00000649048, ENST00000661824, ENST00000741342, ENST00000741343, ENST00000741344, ENST00000741345, ENST00000741346

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000494231 — 3 exons

Exon	Start	End
ENSE00001875242	107923631	107923800
ENSE00004078463	107927873	107928907
ENSE00004078478	107883064	107883306

Expression profiles

Bgee: expression breadth ubiquitous, 109 present calls, max score 67.12.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.1252 / max 41.0648, expressed in 66 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
37801	0.1165	64
37800	0.0067	1
37799	0.0020	2

Top tissues by expression

204 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
cortical plate	UBERON:0005343	67.12	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	66.56	gold quality
skin of hip	UBERON:0001554	60.59	silver quality
buccal mucosa cell	CL:0002336	60.16	gold quality
ventricular zone	UBERON:0003053	59.98	gold quality
ganglionic eminence	UBERON:0004023	57.51	silver quality
right hemisphere of cerebellum	UBERON:0014890	57.31	gold quality
corpus epididymis	UBERON:0004359	57.07	gold quality
cerebellar hemisphere	UBERON:0002245	56.92	gold quality
cerebellar cortex	UBERON:0002129	56.89	gold quality
prefrontal cortex	UBERON:0000451	56.79	gold quality
cerebellum	UBERON:0002037	55.73	gold quality
smooth muscle tissue	UBERON:0001135	55.02	gold quality
Brodmann (1909) area 9	UBERON:0013540	54.30	gold quality
oocyte	CL:0000023	53.83	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	53.41	gold quality
upper leg skin	UBERON:0004262	52.58	silver quality
spinal cord	UBERON:0002240	52.14	gold quality
lymph node	UBERON:0000029	51.84	gold quality
monocyte	CL:0000576	51.29	silver quality
right frontal lobe	UBERON:0002810	51.06	gold quality
frontal cortex	UBERON:0001870	50.99	gold quality
putamen	UBERON:0001874	50.79	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	50.63	gold quality
neocortex	UBERON:0001950	50.18	gold quality
islet of Langerhans	UBERON:0000006	49.64	gold quality
cerebral cortex	UBERON:0000956	48.85	gold quality
gall bladder	UBERON:0002110	48.67	gold quality
brain	UBERON:0000955	48.59	gold quality
nucleus accumbens	UBERON:0001882	48.35	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.45

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Exosomes Containing LINC00636 Inhibit MAPK1 through the miR-450a-2-3p Overexpression in Human Pericardial Fluid and Improve Cardiac Fibrosis in Patients with Atrial Fibrillation. (PMID:34257520)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.