LINC00648

Summary

LINC00648 (long intergenic non-protein coding RNA 648, HGNC:44302) is a long non-coding RNA gene on chromosome 14q21.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:44302
Approved symbol	LINC00648
Name	long intergenic non-protein coding RNA 648
Location	14q21.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000259129
Ensembl biotype	lncRNA
Entrez	100506433
RNAcentral	URS000075E72E — lncRNA, 2903 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 20 — 20 lncRNA

ENST00000553747, ENST00000555985, ENST00000556923, ENST00000557749, ENST00000802535, ENST00000802536, ENST00000802537, ENST00000802538, ENST00000802539, ENST00000802540, ENST00000802541, ENST00000802542, ENST00000802543, ENST00000802544, ENST00000802545, ENST00000802546, ENST00000802547, ENST00000802548, ENST00000802549, ENST00000802550

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000553747 — 2 exons

Exon	Start	End
ENSE00002460759	47789906	47789943
ENSE00002504861	47766686	47766927

Expression profiles

Bgee: expression breadth ubiquitous, 134 present calls, max score 76.15.

Top tissues by expression

228 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	76.15	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	74.31	gold quality
buccal mucosa cell	CL:0002336	72.10	gold quality
ventricular zone	UBERON:0003053	70.40	gold quality
ganglionic eminence	UBERON:0004023	64.11	gold quality
placenta	UBERON:0001987	60.58	gold quality
monocyte	CL:0000576	59.57	gold quality
adrenal tissue	UBERON:0018303	59.03	gold quality
cortex of kidney	UBERON:0001225	58.80	gold quality
germinal epithelium of ovary	UBERON:0001304	58.42	gold quality
cortical plate	UBERON:0005343	56.79	silver quality
mucosa of stomach	UBERON:0001199	56.40	gold quality
left coronary artery	UBERON:0001626	54.99	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	53.78	gold quality
coronary artery	UBERON:0001621	53.52	gold quality
gall bladder	UBERON:0002110	53.34	gold quality
subcutaneous adipose tissue	UBERON:0002190	53.33	gold quality
right atrium auricular region	UBERON:0006631	53.25	gold quality
cardiac atrium	UBERON:0002081	52.80	gold quality
spinal cord	UBERON:0002240	52.47	gold quality
left ovary	UBERON:0002119	52.44	gold quality
ovary	UBERON:0000992	52.25	gold quality
right adrenal gland cortex	UBERON:0035827	52.20	gold quality
hindlimb stylopod muscle	UBERON:0004252	51.92	silver quality
prefrontal cortex	UBERON:0000451	51.76	gold quality
right adrenal gland	UBERON:0001233	51.71	gold quality
right coronary artery	UBERON:0001625	51.61	gold quality
adrenal gland	UBERON:0002369	51.61	gold quality
adenohypophysis	UBERON:0002196	51.58	gold quality
right lobe of thyroid gland	UBERON:0001119	51.40	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	4.20

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Verification of expression of LINC00648 in the serum of lung cancer patients by TCGA database. (PMID:32538754)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.