LINC00654

Summary

LINC00654 (long intergenic non-protein coding RNA 654, HGNC:27154) is a long non-coding RNA gene on chromosome 20p12.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:27154
Approved symbol	LINC00654
Name	long intergenic non-protein coding RNA 654
Location	20p12.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000205181
Ensembl biotype	lncRNA
Entrez	149837
RNAcentral	URS0000A775BD — lncRNA, 6127 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 59 — 59 lncRNA

ENST00000379053, ENST00000450640, ENST00000589201, ENST00000650928, ENST00000654011, ENST00000660858, ENST00000661996, ENST00000663299, ENST00000664106, ENST00000665765, ENST00000794787, ENST00000794788, ENST00000794789, ENST00000794790, ENST00000794791, ENST00000794792, ENST00000794793, ENST00000794794, ENST00000794795, ENST00000794796, ENST00000794797, ENST00000794798, ENST00000794799, ENST00000794800, ENST00000794801, ENST00000794802, ENST00000794803, ENST00000794804, ENST00000794805, ENST00000794806, ENST00000794807, ENST00000794808, ENST00000794809, ENST00000794810, ENST00000794811, ENST00000794812, ENST00000794813, ENST00000794814, ENST00000794815, ENST00000794816, ENST00000794817, ENST00000794818, ENST00000794819, ENST00000794820, ENST00000794821, ENST00000794822, ENST00000794823, ENST00000794824, ENST00000794825, ENST00000794826, ENST00000794827, ENST00000794828, ENST00000794829, ENST00000794830, ENST00000794831, ENST00000794832, ENST00000794833, ENST00000794834, ENST00000794835

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000379053 — 2 exons

Exon	Start	End
ENSE00004178903	5496067	5501863
ENSE00004178957	5504298	5504618

Expression profiles

Bgee: expression breadth ubiquitous, 161 present calls, max score 87.53.

FANTOM5 (CAGE): breadth broad, TPM avg 1.6738 / max 162.3906, expressed in 688 samples.

FANTOM5 promoters (4 alternative TSS)

Promoter ID	TPM avg	Samples expressed
186301	1.6558	687
186302	0.0080	3
186298	0.0055	2
186297	0.0045	3

Top tissues by expression

253 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
left testis	UBERON:0004533	87.53	gold quality
right testis	UBERON:0004534	86.37	gold quality
testis	UBERON:0000473	84.93	gold quality
tibialis anterior	UBERON:0001385	79.30	silver quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	76.73	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	76.15	gold quality
right adrenal gland cortex	UBERON:0035827	73.46	gold quality
ganglionic eminence	UBERON:0004023	73.07	gold quality
cortical plate	UBERON:0005343	73.00	gold quality
stromal cell of endometrium	CL:0002255	72.83	gold quality
ventricular zone	UBERON:0003053	72.68	gold quality
smooth muscle tissue	UBERON:0001135	72.22	gold quality
right adrenal gland	UBERON:0001233	72.19	gold quality
left adrenal gland	UBERON:0001234	71.49	gold quality
islet of Langerhans	UBERON:0000006	71.07	gold quality
ileal mucosa	UBERON:0000331	71.06	gold quality
left adrenal gland cortex	UBERON:0035825	70.70	gold quality
adrenal gland	UBERON:0002369	69.62	gold quality
rectum	UBERON:0001052	69.41	gold quality
adrenal cortex	UBERON:0001235	69.12	gold quality
colonic epithelium	UBERON:0000397	68.44	silver quality
right atrium auricular region	UBERON:0006631	68.02	gold quality
kidney epithelium	UBERON:0004819	67.98	gold quality
prefrontal cortex	UBERON:0000451	67.95	gold quality
apex of heart	UBERON:0002098	67.47	gold quality
heart left ventricle	UBERON:0002084	67.35	gold quality
bone marrow cell	CL:0002092	67.02	silver quality
cardiac atrium	UBERON:0002081	66.98	gold quality
cardiac ventricle	UBERON:0002082	66.45	gold quality
gall bladder	UBERON:0002110	66.15	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	4.51

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.