LINC00658

Summary

LINC00658 (long intergenic non-protein coding RNA 658, HGNC:44315) is a long non-coding RNA gene on chromosome 20p12.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:44315
Approved symbol	LINC00658
Name	long intergenic non-protein coding RNA 658
Location	20p12.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000226995
Ensembl biotype	lncRNA
Entrez	100507629
RNAcentral	URS000075A287 — lncRNA, 1639 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 68 — 68 lncRNA

ENST00000414677, ENST00000420529, ENST00000422352, ENST00000593667, ENST00000599273, ENST00000600157, ENST00000609252, ENST00000651363, ENST00000653249, ENST00000653836, ENST00000653876, ENST00000653999, ENST00000654250, ENST00000654287, ENST00000654309, ENST00000654489, ENST00000654514, ENST00000655376, ENST00000656275, ENST00000656400, ENST00000656534, ENST00000656638, ENST00000656899, ENST00000657133, ENST00000657840, ENST00000658058, ENST00000658725, ENST00000659505, ENST00000660117, ENST00000661909, ENST00000663522, ENST00000663728, ENST00000663916, ENST00000663995, ENST00000664317, ENST00000664467, ENST00000664898, ENST00000664972, ENST00000665203, ENST00000665426, ENST00000665611, ENST00000665791, ENST00000665811, ENST00000666158, ENST00000666637, ENST00000666761, ENST00000666888, ENST00000667166, ENST00000668033, ENST00000668401, ENST00000669038, ENST00000669067, ENST00000669296, ENST00000669585, ENST00000669847, ENST00000670106, ENST00000670531, ENST00000671629, ENST00000794407, ENST00000794408, ENST00000794409, ENST00000794410, ENST00000794411, ENST00000794412, ENST00000794413, ENST00000794414, ENST00000794415, ENST00000794416

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000414677 — 3 exons

Exon	Start	End
ENSE00003845184	5432543	5432638
ENSE00003866502	5431954	5432372
ENSE00003875121	5445504	5445725

Expression profiles

Bgee: expression breadth ubiquitous, 104 present calls, max score 95.08.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0980 / max 115.9288, expressed in 5 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
186295	0.0596	4
186296	0.0384	4

Top tissues by expression

206 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sperm	CL:0000019	95.08	gold quality
left testis	UBERON:0004533	91.02	gold quality
right testis	UBERON:0004534	90.45	gold quality
testis	UBERON:0000473	87.93	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.92	gold quality
adult organism	UBERON:0007023	73.22	gold quality
pancreatic ductal cell	CL:0002079	71.54	silver quality
ileal mucosa	UBERON:0000331	64.67	silver quality
tibialis anterior	UBERON:0001385	62.90	silver quality
ganglionic eminence	UBERON:0004023	60.00	gold quality
right lobe of liver	UBERON:0001114	56.89	gold quality
deltoid	UBERON:0001476	56.75	gold quality
epithelial cell of pancreas	CL:0000083	56.05	gold quality
cardiac muscle of right atrium	UBERON:0003379	54.34	gold quality
left ventricle myocardium	UBERON:0006566	54.23	gold quality
kidney epithelium	UBERON:0004819	53.93	gold quality
upper arm skin	UBERON:0004263	53.52	gold quality
endothelial cell	CL:0000115	52.17	gold quality
prefrontal cortex	UBERON:0000451	51.03	gold quality
monocyte	CL:0000576	50.89	gold quality
vermiform appendix	UBERON:0001154	50.31	gold quality
myocardium	UBERON:0002349	50.25	gold quality
blood	UBERON:0000178	49.82	gold quality
right adrenal gland cortex	UBERON:0035827	49.38	gold quality
muscle of leg	UBERON:0001383	49.30	gold quality
middle temporal gyrus	UBERON:0002771	48.84	gold quality
islet of Langerhans	UBERON:0000006	48.81	gold quality
gastrocnemius	UBERON:0001388	48.68	gold quality
Brodmann (1909) area 9	UBERON:0013540	48.65	gold quality
putamen	UBERON:0001874	48.60	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.07

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.