LINC00677

Summary

LINC00677 (long intergenic non-protein coding RNA 677, HGNC:20121) is a long non-coding RNA gene on chromosome 14q32.32.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:20121
Approved symbol	LINC00677
Name	long intergenic non-protein coding RNA 677
Location	14q32.32
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000259717
Ensembl biotype	lncRNA
Entrez	105370683
RNAcentral	URS0000A76680 — lncRNA, 484 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000558224, ENST00000560742, ENST00000701671, ENST00000729014, ENST00000729015, ENST00000729016

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000558224 — 2 exons

Exon	Start	End
ENSE00002537924	103120847	103121031
ENSE00004056108	103122609	103123094

Expression profiles

Bgee: expression breadth ubiquitous, 112 present calls, max score 97.84.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0762 / max 33.0053, expressed in 23 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
145065	0.0762	23

Top tissues by expression

112 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	97.84	gold quality
granulocyte	CL:0000094	77.93	gold quality
bone marrow cell	CL:0002092	76.54	gold quality
left testis	UBERON:0004533	74.96	gold quality
testis	UBERON:0000473	74.01	gold quality
monocyte	CL:0000576	73.77	gold quality
leukocyte	CL:0000738	73.22	gold quality
right testis	UBERON:0004534	71.92	gold quality
blood	UBERON:0000178	69.43	gold quality
right lung	UBERON:0002167	67.10	gold quality
bone marrow	UBERON:0002371	65.95	gold quality
duodenum	UBERON:0002114	63.28	gold quality
right coronary artery	UBERON:0001625	61.43	gold quality
metanephros cortex	UBERON:0010533	60.31	gold quality
cortex of kidney	UBERON:0001225	59.44	gold quality
placenta	UBERON:0001987	59.27	gold quality
vermiform appendix	UBERON:0001154	59.12	gold quality
spleen	UBERON:0002106	58.60	gold quality
upper lobe of left lung	UBERON:0008952	58.25	gold quality
lung	UBERON:0002048	58.21	gold quality
gall bladder	UBERON:0002110	57.62	gold quality
left adrenal gland cortex	UBERON:0035825	56.82	gold quality
subcutaneous adipose tissue	UBERON:0002190	55.79	gold quality
adipose tissue	UBERON:0001013	55.59	gold quality
smooth muscle tissue	UBERON:0001135	55.48	gold quality
omental fat pad	UBERON:0010414	55.31	gold quality
kidney	UBERON:0002113	55.06	gold quality
urinary bladder	UBERON:0001255	54.37	gold quality
thoracic mammary gland	UBERON:0005200	54.17	gold quality
liver	UBERON:0002107	53.88	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.65

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.