LINC00682

Summary

LINC00682 (long intergenic non-protein coding RNA 682, HGNC:44466) is a long non-coding RNA gene on chromosome 4p13.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:44466
Approved symbol	LINC00682
Name	long intergenic non-protein coding RNA 682
Location	4p13
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000245870
Ensembl biotype	lncRNA
Entrez	101927074
RNAcentral	URS000075BB76 — lncRNA, 1440 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 9 — 9 lncRNA

ENST00000498940, ENST00000499082, ENST00000504870, ENST00000637677, ENST00000670465, ENST00000716828, ENST00000716829, ENST00000716830, ENST00000716831

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000498940 — 2 exons

Exon	Start	End
ENSE00001977115	41881486	41881843
ENSE00001991892	41879547	41880813

Expression profiles

Bgee: expression breadth ubiquitous, 112 present calls, max score 85.92.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.4204 / max 405.4999, expressed in 31 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
51956	0.3953	28
51957	0.0251	5

Top tissues by expression

212 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	85.92	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.94	gold quality
adrenal tissue	UBERON:0018303	68.05	gold quality
muscle layer of sigmoid colon	UBERON:0035805	66.64	gold quality
cortical plate	UBERON:0005343	65.55	gold quality
colonic epithelium	UBERON:0000397	63.35	silver quality
adrenal gland	UBERON:0002369	62.54	gold quality
left adrenal gland cortex	UBERON:0035825	61.01	gold quality
right adrenal gland	UBERON:0001233	60.97	gold quality
left adrenal gland	UBERON:0001234	60.34	gold quality
mucosa of transverse colon	UBERON:0004991	60.14	gold quality
transverse colon	UBERON:0001157	59.42	gold quality
colon	UBERON:0001155	59.28	gold quality
right adrenal gland cortex	UBERON:0035827	58.99	gold quality
large intestine	UBERON:0000059	58.57	gold quality
adrenal cortex	UBERON:0001235	58.38	gold quality
intestine	UBERON:0000160	58.01	gold quality
smooth muscle tissue	UBERON:0001135	57.69	gold quality
monocyte	CL:0000576	57.14	gold quality
lower esophagus muscularis layer	UBERON:0035833	57.06	gold quality
lower esophagus	UBERON:0013473	57.00	gold quality
rectum	UBERON:0001052	56.80	gold quality
stomach	UBERON:0000945	56.34	gold quality
body of stomach	UBERON:0001161	55.51	gold quality
small intestine Peyer’s patch	UBERON:0003454	54.86	gold quality
esophagus	UBERON:0001043	54.77	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	54.26	gold quality
small intestine	UBERON:0002108	54.21	gold quality
islet of Langerhans	UBERON:0000006	53.59	gold quality
endothelial cell	CL:0000115	53.39	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.27

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Results show that low DNA methylation levels of LINC00682, MAD1L1, and LINE-2 was strongly correlated with hepatocellular carcinomas recurrence, patient disease-free survival, and/or overall survival. (PMID:26138747)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.