LINC00685

Summary

LINC00685 (long intergenic non-protein coding RNA 685, HGNC:27560) is a long non-coding RNA gene on chromosome Xp22.33 and Yp11.32.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:27560
Approved symbol	LINC00685
Name	long intergenic non-protein coding RNA 685
Location	Xp22.33 and Yp11.32
Locus type	RNA, long non-coding
Status	Approved
Aliases	OTTHUMT00000055574
Ensembl gene	ENSG00000226179
Ensembl biotype	lncRNA
Entrez	283981
RNAcentral	URS0000759D41 — lncRNA, 1532 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000391707

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000391707 — 2 exons

Exon	Start	End
ENSE00001675006	320990	321248
ENSE00001778583	321683	321851

Expression profiles

Bgee: expression breadth ubiquitous, 192 present calls, max score 95.99.

Top tissues by expression

249 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right hemisphere of cerebellum	UBERON:0014890	95.99	gold quality
cerebellar hemisphere	UBERON:0002245	95.96	gold quality
cerebellar cortex	UBERON:0002129	95.82	gold quality
cerebellum	UBERON:0002037	94.25	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	92.05	gold quality
amygdala	UBERON:0001876	91.53	gold quality
anterior cingulate cortex	UBERON:0009835	91.03	gold quality
putamen	UBERON:0001874	90.61	gold quality
lower esophagus mucosa	UBERON:0035834	90.07	gold quality
spinal cord	UBERON:0002240	89.99	gold quality
right frontal lobe	UBERON:0002810	89.53	gold quality
Brodmann (1909) area 9	UBERON:0013540	89.43	gold quality
caudate nucleus	UBERON:0001873	89.40	gold quality
nucleus accumbens	UBERON:0001882	89.33	gold quality
adenohypophysis	UBERON:0002196	88.91	gold quality
hypothalamus	UBERON:0001898	88.63	gold quality
pituitary gland	UBERON:0000007	87.20	gold quality
apex of heart	UBERON:0002098	87.03	gold quality
mucosa of transverse colon	UBERON:0004991	86.95	gold quality
right ovary	UBERON:0002118	86.44	gold quality
left ovary	UBERON:0002119	86.40	gold quality
sural nerve	UBERON:0015488	85.98	gold quality
spleen	UBERON:0002106	85.66	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	85.57	gold quality
left lobe of thyroid gland	UBERON:0001120	85.56	gold quality
granulocyte	CL:0000094	85.55	gold quality
left uterine tube	UBERON:0001303	85.55	gold quality
right lobe of liver	UBERON:0001114	85.28	gold quality
right lobe of thyroid gland	UBERON:0001119	85.28	gold quality
ectocervix	UBERON:0012249	85.05	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.00

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.