LINC00686

Summary

LINC00686 (long intergenic non-protein coding RNA 686, HGNC:16221) is a long non-coding RNA gene on chromosome 20q13.33.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:16221
Approved symbol	LINC00686
Name	long intergenic non-protein coding RNA 686
Location	20q13.33
Locus type	RNA, long non-coding
Status	Approved
Aliases	bA93B14.2
Ensembl gene	ENSG00000237687
Ensembl biotype	lncRNA
Entrez	140865
RNAcentral	URS0002A38C7C — lncRNA, 591 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000435412

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000435412 — 2 exons

Exon	Start	End
ENSE00004046256	62694810	62695263
ENSE00004046257	62700389	62700525

Expression profiles

Bgee: expression breadth broad, 48 present calls, max score 64.40.

Top tissues by expression

48 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
bone marrow	UBERON:0002371	64.40	gold quality
blood	UBERON:0000178	63.41	gold quality
superior frontal gyrus	UBERON:0002661	59.13	gold quality
monocyte	CL:0000576	57.02	gold quality
fundus of stomach	UBERON:0001160	53.77	gold quality
left uterine tube	UBERON:0001303	53.58	gold quality
right lobe of liver	UBERON:0001114	53.55	gold quality
prefrontal cortex	UBERON:0000451	52.53	gold quality
fallopian tube	UBERON:0003889	52.29	gold quality
muscle layer of sigmoid colon	UBERON:0035805	51.74	gold quality
Brodmann (1909) area 9	UBERON:0013540	51.46	gold quality
substantia nigra	UBERON:0002038	51.17	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	50.41	gold quality
gastrocnemius	UBERON:0001388	49.72	gold quality
heart left ventricle	UBERON:0002084	49.69	gold quality
body of stomach	UBERON:0001161	49.19	gold quality
transverse colon	UBERON:0001157	49.16	gold quality
Ammon’s horn	UBERON:0001954	48.02	gold quality
omental fat pad	UBERON:0010414	47.58	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	47.49	gold quality
spleen	UBERON:0002106	47.34	gold quality
hypothalamus	UBERON:0001898	46.50	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	46.43	gold quality
brain	UBERON:0000955	46.20	gold quality
granulocyte	CL:0000094	46.11	silver quality
amygdala	UBERON:0001876	45.47	gold quality
ascending aorta	UBERON:0001496	44.68	gold quality
frontal cortex	UBERON:0001870	44.59	gold quality
lower esophagus muscularis layer	UBERON:0035833	44.42	gold quality
anterior cingulate cortex	UBERON:0009835	44.18	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.22

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.