LINC00696

Summary

LINC00696 (long intergenic non-protein coding RNA 696, HGNC:34426) is a long non-coding RNA gene on chromosome 3p21.1.

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:34426
Approved symbol	LINC00696
Name	long intergenic non-protein coding RNA 696
Location	3p21.1
Locus type	RNA, long non-coding
Status	Approved
Entrez	100128378
RNAcentral	URS0000759FB8 — lncRNA, 3019 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 0

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

None — 0 exons

Expression profiles

Top tissues by expression

0 total, by Bgee expression score (0-100, higher = more expressed):

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Protein identifiers

Putative uncharacterized protein encoded by LINC00696 — Q6ZRV3 (reviewed: Q6ZRV3)

All UniProt accessions (0):

UniProt curated annotations — full annotation on UniProt →

RefSeq proteins (0): (*=MANE)

Domains & families (InterPro)

UniProt features (3 total): chain 1, region of interest 1, compositionally biased region 1

Structure

Experimental structures (PDB)

0 structures.

Predicted structure (AlphaFold)

Model	pLDDT	Fraction very-high
AF-Q6ZRV3-F1	31.61	0.00

Function

Pathways and Gene Ontology

Reactome pathways

0 pathways

MSigDB gene sets: 0 (showing top):

GO Biological Process (0):

GO Molecular Function (0):

GO Cellular Component (0):

Protein interactions and networks

STRING

0 interactions, top by confidence (×1000):

IntAct

2 interactions, top by confidence:

A	B	Type	Score
MAP1LC3A	LINC00696	psi-mi:“MI:0407”(direct interaction)	0.440

ESM2 similar proteins: A1L4Q6, A4D1N5, A4D250, A6NM66, B1ANY3, C0HM98, F2Z3F1, J3KSC0, O15544, O71302, O93195, O95411, P0C686, P20977, P24026, P49671, P87743, Q0VFX4, Q14695, Q2M3A8, Q4R3X9, Q5SR53, Q5SWW7, Q67923, Q69604, Q6DGF6, Q6ZP68, Q6ZRV3, Q6ZTY9, Q6ZUL3, Q6ZVU0, Q7Z4H9, Q80IU8, Q81163, Q8JMY5, Q8JMZ5, Q8N4M7, Q8N5N4, Q8N814, Q96LS8

SIGNOR signaling

0 interactions.

Disease & clinical

Clinical variants and AI predictions

ClinVar

0 variants total. Per-class counts are floors (≥ shown; pagination cap):

Classification	Count (floor)
Pathogenic	0
Likely pathogenic	0
Uncertain significance	0
Likely benign	0
Benign	0

Top pathogenic / likely-pathogenic (0)

SpliceAI

0 predictions. Top by Δscore:

AlphaMissense

0 scored. Top likely-pathogenic:

dbSNP variants (sampled 300 via entrez): RS1000057843 (3:52063647 C>T), RS1000639564 (3:52067049 G>A), RS1002082286 (3:52062319 G>T), RS1002270046 (3:52064142 G>GAC), RS1002638338 (3:52065775 C>A), RS1002749685 (3:52065334 G>A), RS1003192346 (3:52065532 C>T), RS1003784502 (3:52064231 A>G), RS1004139721 (3:52066216 C>G,T), RS1004156937 (3:52063914 C>A,T), RS1004309786 (3:52066374 T>C), RS1004447700 (3:52066998 G>A,C), RS1004820755 (3:52066734 T>C,G), RS1005184174 (3:52063383 C>A,G), RS1005960885 (3:52062450 G>C)

Disease associations

OMIM: gene `` | disease phenotypes:

GenCC curated gene-disease

Mondo (0):

Orphanet (0):

HPO phenotypes

0 total (0 of 0 shown, HPO-id order):

GWAS associations

0 associations (top):

Drugs & pharmacology

Drug and pharmacology data

Is drug target: no

PharmGKB: 1 entry (VIP=true, CPIC=false)

CTD chemical–gene interactions

3 total (human), top 3 by PubMed support.

Chemical	Actions (top 5)	PubMed papers
Benzo(a)pyrene	decreases methylation	1
Valproic Acid	increases methylation	1
Permethrin	increases expression	1

Clinical trials (associated diseases)

0 trials via MONDO — disease-level, not drug-specific.