LINC00703

Summary

LINC00703 (long intergenic non-protein coding RNA 703, HGNC:44677) is a long non-coding RNA gene on chromosome 10p15.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:44677
Approved symbol	LINC00703
Name	long intergenic non-protein coding RNA 703
Location	10p15.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000224382
Ensembl biotype	lncRNA
Entrez	100507059
RNAcentral	URS000075F11B — lncRNA, 2493 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000434902, ENST00000454152, ENST00000655424, ENST00000731885, ENST00000731886, ENST00000731887

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000434902 — 2 exons

Exon	Start	End
ENSE00001663947	4406502	4406573
ENSE00001733677	4408455	4409251

Expression profiles

Bgee: expression breadth broad, 48 present calls, max score 74.95.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0099 / max 7.6684, expressed in 4 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
103585	0.0099	4

Top tissues by expression

177 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	74.95	gold quality
buccal mucosa cell	CL:0002336	73.93	silver quality
cortical plate	UBERON:0005343	67.69	gold quality
ventricular zone	UBERON:0003053	65.05	gold quality
ganglionic eminence	UBERON:0004023	64.83	gold quality
left testis	UBERON:0004533	63.72	gold quality
right testis	UBERON:0004534	62.72	gold quality
testis	UBERON:0000473	61.62	gold quality
prefrontal cortex	UBERON:0000451	50.61	gold quality
stromal cell of endometrium	CL:0002255	50.48	silver quality
gall bladder	UBERON:0002110	48.77	gold quality
monocyte	CL:0000576	47.68	silver quality
body of pancreas	UBERON:0001150	45.81	gold quality
islet of Langerhans	UBERON:0000006	45.40	gold quality
calcaneal tendon	UBERON:0003701	45.17	silver quality
gastrocnemius	UBERON:0001388	45.11	gold quality
neocortex	UBERON:0001950	43.94	gold quality
tibial nerve	UBERON:0001323	43.82	gold quality
Brodmann (1909) area 9	UBERON:0013540	43.45	silver quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	43.37	gold quality
anatomical system	UBERON:0000467	43.34	gold quality
lower esophagus muscularis layer	UBERON:0035833	43.31	gold quality
multicellular organism	UBERON:0000468	43.12	gold quality
material anatomical entity	UBERON:0000465	43.10	gold quality
frontal cortex	UBERON:0001870	43.03	silver quality
lymph node	UBERON:0000029	42.80	gold quality
tibial artery	UBERON:0007610	42.71	silver quality
secondary oocyte	CL:0000655	42.57	gold quality
esophagus	UBERON:0001043	42.45	silver quality
pancreas	UBERON:0001264	42.43	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	2.95

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Linc00703 suppresses non-small cell lung cancer progression by modulating CyclinD1/CDK4 expression. (PMID:32572878)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.