LINC00842

Summary

LINC00842 (long intergenic non-protein coding RNA 842, HGNC:44989) is a long non-coding RNA gene on chromosome 10q11.22.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:44989
Approved symbol	LINC00842
Name	long intergenic non-protein coding RNA 842
Location	10q11.22
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000285294
Ensembl biotype	lncRNA
Entrez	643650
RNAcentral	URS000075E9B4 — lncRNA, 2872 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 6 — 6 lncRNA

ENST00000614356, ENST00000716464, ENST00000716465, ENST00000716466, ENST00000716467, ENST00000716468

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000614356 — 4 exons

Exon	Start	End
ENSE00003731003	46398362	46398793
ENSE00003736069	46450353	46450471
ENSE00003738932	46450048	46450174
ENSE00003741208	46451113	46453306

Expression profiles

Bgee: expression breadth ubiquitous, 126 present calls, max score 68.20.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.1867 / max 23.6924, expressed in 90 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
104805	0.1867	90

Top tissues by expression

221 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
muscle layer of sigmoid colon	UBERON:0035805	68.20	gold quality
skin of abdomen	UBERON:0001416	67.30	gold quality
colonic epithelium	UBERON:0000397	65.30	silver quality
skin of leg	UBERON:0001511	64.27	gold quality
omental fat pad	UBERON:0010414	63.11	gold quality
peritoneum	UBERON:0002358	63.05	gold quality
cortical plate	UBERON:0005343	62.87	gold quality
zone of skin	UBERON:0000014	62.77	gold quality
adipose tissue of abdominal region	UBERON:0007808	61.86	gold quality
right lung	UBERON:0002167	60.51	gold quality
germinal epithelium of ovary	UBERON:0001304	59.07	silver quality
colon	UBERON:0001155	58.27	gold quality
large intestine	UBERON:0000059	57.56	gold quality
upper lobe of left lung	UBERON:0008952	57.03	gold quality
transverse colon	UBERON:0001157	56.26	gold quality
intestine	UBERON:0000160	56.04	gold quality
upper lobe of lung	UBERON:0008948	55.23	gold quality
smooth muscle tissue	UBERON:0001135	55.10	gold quality
islet of Langerhans	UBERON:0000006	52.82	gold quality
rectum	UBERON:0001052	52.38	gold quality
prefrontal cortex	UBERON:0000451	51.94	gold quality
left ovary	UBERON:0002119	51.81	gold quality
right atrium auricular region	UBERON:0006631	51.57	gold quality
small intestine	UBERON:0002108	51.49	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	51.32	gold quality
cardiac atrium	UBERON:0002081	51.23	gold quality
pancreas	UBERON:0001264	51.17	gold quality
small intestine Peyer’s patch	UBERON:0003454	51.17	gold quality
lung	UBERON:0002048	51.14	gold quality
adipose tissue	UBERON:0001013	51.11	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.99

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 2)

• LncRNA ELIT-1 (LINC00842) is a positive regulator of TGFbeta/Smad3 signaling and epithelial-mesenchymal transition.ELIT-1 expression is related to prognosis in gastric cancers and lung adenocarcinoma. (PMID:30952633)
• LINC00842 inactivates transcription co-regulator PGC-1alpha to promote pancreatic cancer malignancy through metabolic remodelling. (PMID:34158490)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.