LINC00852

Summary

LINC00852 (long intergenic non-protein coding RNA 852, HGNC:29904) is a long non-coding RNA gene on chromosome 3p25.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:29904
Approved symbol	LINC00852
Name	long intergenic non-protein coding RNA 852
Location	3p25.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	NAG73, GHRL-AS2
Ensembl gene	ENSG00000231177
Ensembl biotype	lncRNA
Entrez	84657
RNAcentral	URS0000759B4D — lncRNA, 1345 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000475197, ENST00000538717

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000475197 — 1 exons

Exon	Start	End
ENSE00001935342	10284419	10285746

Expression profiles

Bgee: expression breadth ubiquitous, 156 present calls, max score 81.04.

Top tissues by expression

243 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
granulocyte	CL:0000094	81.04	gold quality
bone marrow cell	CL:0002092	80.04	gold quality
monocyte	CL:0000576	75.36	gold quality
leukocyte	CL:0000738	75.36	gold quality
sural nerve	UBERON:0015488	70.00	gold quality
colonic epithelium	UBERON:0000397	69.43	gold quality
left uterine tube	UBERON:0001303	67.87	gold quality
stromal cell of endometrium	CL:0002255	67.15	gold quality
mucosa of transverse colon	UBERON:0004991	66.54	gold quality
calcaneal tendon	UBERON:0003701	66.14	gold quality
small intestine Peyer’s patch	UBERON:0003454	65.45	gold quality
spleen	UBERON:0002106	64.97	gold quality
mucosa of stomach	UBERON:0001199	64.82	gold quality
skin of leg	UBERON:0001511	64.53	gold quality
skin of abdomen	UBERON:0001416	64.33	gold quality
transverse colon	UBERON:0001157	63.89	gold quality
hindlimb stylopod muscle	UBERON:0004252	63.75	gold quality
left lobe of thyroid gland	UBERON:0001120	63.52	gold quality
descending thoracic aorta	UBERON:0002345	63.36	gold quality
upper lobe of left lung	UBERON:0008952	63.32	gold quality
right lobe of thyroid gland	UBERON:0001119	63.23	gold quality
small intestine	UBERON:0002108	62.91	gold quality
body of stomach	UBERON:0001161	62.82	gold quality
omental fat pad	UBERON:0010414	62.80	gold quality
peritoneum	UBERON:0002358	62.74	gold quality
thoracic aorta	UBERON:0001515	62.70	gold quality
right coronary artery	UBERON:0001625	62.66	gold quality
ascending aorta	UBERON:0001496	62.50	gold quality
ventricular zone	UBERON:0003053	62.47	gold quality
blood	UBERON:0000178	62.39	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.67

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 5)

• Exosome-transmitted linc00852 associated with receptor tyrosine kinase AXL dysregulates the proliferation and invasion of osteosarcoma. (PMID:32673448)
• Overexpression of LINC00852 promotes prostate cancer cell proliferation and metastasis. (PMID:33128330)
• LINC00852 promotes the proliferation and invasion of ovarian cancer cells by competitively binding with miR-140-3p to regulate AGTR1 expression. (PMID:34496800)
• Linc00852 from cisplatin-resistant gastric cancer cell-derived exosomes regulates COMMD7 to promote cisplatin resistance of recipient cells through microRNA-514a-5p. (PMID:35088190)
• The LINC00852/miR-29a-3p/JARID2 axis regulates the proliferation and invasion of prostate cancer cell. (PMID:36471281)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.