LINC00861

Summary

LINC00861 (long intergenic non-protein coding RNA 861, HGNC:45133) is a long non-coding RNA gene on chromosome 8q24.13.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:45133
Approved symbol	LINC00861
Name	long intergenic non-protein coding RNA 861
Location	8q24.13
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000245164
Ensembl biotype	lncRNA
Entrez	100130231
RNAcentral	URS0000759C83 — lncRNA, 5338 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 27 — 27 lncRNA

ENST00000500989, ENST00000517869, ENST00000518964, ENST00000522865, ENST00000651482, ENST00000651667, ENST00000652311, ENST00000661778, ENST00000662179, ENST00000689131, ENST00000691489, ENST00000702373, ENST00000843696, ENST00000843697, ENST00000843698, ENST00000843699, ENST00000843700, ENST00000843701, ENST00000843702, ENST00000843703, ENST00000843704, ENST00000843705, ENST00000843706, ENST00000843707, ENST00000843708, ENST00000843709, ENST00000843710

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000500989 — 2 exons

Exon	Start	End
ENSE00004269813	125941129	125946182
ENSE00004269816	125950914	125951256

Expression profiles

Bgee: expression breadth ubiquitous, 124 present calls, max score 92.76.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 9.0721 / max 1011.8723, expressed in 164 samples.

FANTOM5 promoters (6 alternative TSS)

Promoter ID	TPM avg	Samples expressed
94811	4.2775	117
94813	2.6038	103
94812	1.4394	86
94815	0.5261	71
94814	0.1453	48
94810	0.0801	44

Top tissues by expression

124 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
granulocyte	CL:0000094	92.76	gold quality
lymph node	UBERON:0000029	91.38	gold quality
blood	UBERON:0000178	89.78	gold quality
vermiform appendix	UBERON:0001154	88.61	gold quality
spleen	UBERON:0002106	83.47	gold quality
bone marrow cell	CL:0002092	79.20	gold quality
tonsil	UBERON:0002372	77.73	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	77.04	gold quality
bone marrow	UBERON:0002371	74.93	gold quality
colonic epithelium	UBERON:0000397	71.25	silver quality
gall bladder	UBERON:0002110	70.35	gold quality
rectum	UBERON:0001052	69.70	gold quality
small intestine Peyer’s patch	UBERON:0003454	69.13	gold quality
mucosa of transverse colon	UBERON:0004991	68.70	gold quality
small intestine	UBERON:0002108	68.52	gold quality
leukocyte	CL:0000738	65.63	gold quality
lung	UBERON:0002048	65.63	gold quality
cortical plate	UBERON:0005343	65.63	gold quality
right coronary artery	UBERON:0001625	65.48	gold quality
upper lobe of left lung	UBERON:0008952	65.23	gold quality
liver	UBERON:0002107	64.51	gold quality
monocyte	CL:0000576	63.15	gold quality
placenta	UBERON:0001987	62.02	gold quality
duodenum	UBERON:0002114	61.87	gold quality
right lung	UBERON:0002167	61.63	gold quality
right lobe of liver	UBERON:0001114	61.51	gold quality
urinary bladder	UBERON:0001255	61.46	gold quality
muscle tissue	UBERON:0002385	60.96	gold quality
endometrium	UBERON:0001295	60.66	gold quality
sural nerve	UBERON:0015488	60.42	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	20.40

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• LINC00861 inhibits the progression of cervical cancer cells by functioning as a ceRNA for miR513b5p and regulating the PTEN/AKT/mTOR signaling pathway. (PMID:33179755)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.