LINC00869

Summary

LINC00869 (long intergenic non-protein coding RNA 869, HGNC:29050) is a unprocessed pseudogene on chromosome 1q21.2.

Predicted to enable triplet codon-amino acid adaptor activity. Predicted to be involved in translation.

Source: NCBI Gene 57234 — RefSeq curated summary.

At a glance

• Gene type: non-coding (transcribed_unprocessed_pseudogene) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:29050
Approved symbol	LINC00869
Name	long intergenic non-protein coding RNA 869
Location	1q21.2
Locus type	RNA, long non-coding
Status	Approved
Aliases	KIAA0493
Ensembl gene	ENSG00000277147
Ensembl biotype	transcribed_unprocessed_pseudogene
Entrez	57234

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 transcribed_unprocessed_pseudogene

ENST00000643247

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000643247 — 6 exons

Exon	Start	End
ENSE00001707319	149660854	149661089
ENSE00003743386	149665082	149665133
ENSE00003815852	149665957	149666124
ENSE00003823339	149669189	149669321
ENSE00003826207	149658152	149658254
ENSE00003828226	149655731	149655908

Expression profiles

Bgee: expression breadth ubiquitous, 171 present calls, max score 94.62.

Top tissues by expression

249 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
granulocyte	CL:0000094	94.62	gold quality
colonic epithelium	UBERON:0000397	90.81	gold quality
bone marrow cell	CL:0002092	90.36	gold quality
right lobe of liver	UBERON:0001114	89.92	gold quality
body of pancreas	UBERON:0001150	88.42	gold quality
muscle layer of sigmoid colon	UBERON:0035805	87.56	gold quality
Brodmann (1909) area 9	UBERON:0013540	87.06	gold quality
right ovary	UBERON:0002118	86.97	gold quality
adenohypophysis	UBERON:0002196	86.93	gold quality
left ovary	UBERON:0002119	86.90	gold quality
cerebellar hemisphere	UBERON:0002245	86.72	gold quality
right hemisphere of cerebellum	UBERON:0014890	86.65	gold quality
cerebellar cortex	UBERON:0002129	86.53	gold quality
right frontal lobe	UBERON:0002810	86.29	gold quality
right uterine tube	UBERON:0001302	86.18	gold quality
hypothalamus	UBERON:0001898	86.00	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	85.96	gold quality
vermiform appendix	UBERON:0001154	85.82	gold quality
anterior cingulate cortex	UBERON:0009835	85.76	gold quality
mucosa of stomach	UBERON:0001199	85.75	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	85.74	gold quality
right coronary artery	UBERON:0001625	85.64	gold quality
mucosa of transverse colon	UBERON:0004991	85.38	gold quality
pancreas	UBERON:0001264	85.26	gold quality
small intestine Peyer’s patch	UBERON:0003454	85.22	gold quality
prefrontal cortex	UBERON:0000451	84.94	gold quality
nucleus accumbens	UBERON:0001882	84.82	gold quality
leukocyte	CL:0000738	84.63	gold quality
amygdala	UBERON:0001876	84.61	gold quality
body of stomach	UBERON:0001161	84.57	gold quality

Single-cell (SCXA)

Detected in 10 experiment(s), a significant marker in 7.

Experiment	Marker?	Max mean expression
E-HCAD-4	yes	99.44
E-MTAB-8142	yes	51.13
E-CURD-122	yes	41.64
E-HCAD-8	yes	36.31
E-HCAD-1	yes	34.43
E-CURD-88	yes	18.13
E-ANND-3	yes	7.37
E-CURD-95	no	489.13
E-MTAB-8911	no	467.70
E-HCAD-13	no	275.56

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• LINC00869 Promotes Hepatocellular Carcinoma Metastasis via Protrusion Formation. (PMID:37934195)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.