LINC00870

Summary

LINC00870 (long intergenic non-protein coding RNA 870, HGNC:27319) is a long non-coding RNA gene on chromosome 3p13.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:27319
Approved symbol	LINC00870
Name	long intergenic non-protein coding RNA 870
Location	3p13
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000243083
Ensembl biotype	lncRNA
Entrez	201617
RNAcentral	URS000075CFA6 — lncRNA, 2700 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 31 — 31 lncRNA

ENST00000469178, ENST00000473713, ENST00000485404, ENST00000650568, ENST00000661020, ENST00000664354, ENST00000701139, ENST00000811956, ENST00000811957, ENST00000811958, ENST00000811959, ENST00000811960, ENST00000811961, ENST00000811962, ENST00000811963, ENST00000811964, ENST00000811965, ENST00000811966, ENST00000811967, ENST00000811968, ENST00000811969, ENST00000811970, ENST00000811971, ENST00000811972, ENST00000811973, ENST00000811974, ENST00000811975, ENST00000811976, ENST00000811977, ENST00000811978, ENST00000811979

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000469178 — 3 exons

Exon	Start	End
ENSE00001812529	72171909	72172099
ENSE00001886102	72152759	72152918
ENSE00001907777	72159361	72159467

Expression profiles

Bgee: expression breadth ubiquitous, 115 present calls, max score 71.17.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.1422 / max 8.4742, expressed in 60 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
37311	0.1230	49
37310	0.0192	11

Top tissues by expression

207 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right lobe of liver	UBERON:0001114	71.17	gold quality
stromal cell of endometrium	CL:0002255	65.22	gold quality
liver	UBERON:0002107	62.68	gold quality
islet of Langerhans	UBERON:0000006	60.02	gold quality
corpus callosum	UBERON:0002336	58.95	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	58.25	gold quality
ganglionic eminence	UBERON:0004023	57.78	gold quality
hindlimb stylopod muscle	UBERON:0004252	57.42	silver quality
prefrontal cortex	UBERON:0000451	56.31	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	56.31	gold quality
spinal cord	UBERON:0002240	54.83	gold quality
putamen	UBERON:0001874	54.57	gold quality
pancreas	UBERON:0001264	54.24	gold quality
adult mammalian kidney	UBERON:0000082	53.31	gold quality
rectum	UBERON:0001052	53.04	gold quality
substantia nigra	UBERON:0002038	51.85	gold quality
monocyte	CL:0000576	51.63	silver quality
caudate nucleus	UBERON:0001873	51.38	gold quality
mucosa of transverse colon	UBERON:0004991	50.82	gold quality
vermiform appendix	UBERON:0001154	50.50	gold quality
calcaneal tendon	UBERON:0003701	50.50	silver quality
amygdala	UBERON:0001876	50.49	gold quality
hypothalamus	UBERON:0001898	50.42	gold quality
nucleus accumbens	UBERON:0001882	50.40	gold quality
midbrain	UBERON:0001891	50.40	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	50.25	gold quality
frontal cortex	UBERON:0001870	49.98	gold quality
pituitary gland	UBERON:0000007	49.69	gold quality
adrenal tissue	UBERON:0018303	49.60	silver quality
kidney	UBERON:0002113	49.25	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.60

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• LINC00870 regulates Th1/Th2 via the JAK/STAT pathway in peripheral blood mononuclear cells infected with Mycobacterium tuberculosis. (PMID:34407915)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.