LINC00877

Summary

LINC00877 (long intergenic non-protein coding RNA 877, HGNC:27706) is a long non-coding RNA gene on chromosome 3p13.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:27706
Approved symbol	LINC00877
Name	long intergenic non-protein coding RNA 877
Location	3p13
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000241163
Ensembl biotype	lncRNA
Entrez	285286
RNAcentral	URS000075A347 — lncRNA, 2315 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 87 — 87 lncRNA

ENST00000462492, ENST00000464271, ENST00000468646, ENST00000469218, ENST00000470712, ENST00000481148, ENST00000488545, ENST00000498432, ENST00000608654, ENST00000618391, ENST00000626474, ENST00000656335, ENST00000658297, ENST00000660632, ENST00000661666, ENST00000662591, ENST00000664410, ENST00000664517, ENST00000665453, ENST00000666244, ENST00000668168, ENST00000668763, ENST00000671527, ENST00000686889, ENST00000687511, ENST00000689824, ENST00000690747, ENST00000692457, ENST00000692617, ENST00000693126, ENST00000701651, ENST00000701668, ENST00000702403, ENST00000811794, ENST00000811795, ENST00000811796, ENST00000811797, ENST00000811798, ENST00000811799, ENST00000811800, ENST00000811801, ENST00000811802, ENST00000811803, ENST00000811804, ENST00000811805, ENST00000811806, ENST00000811807, ENST00000811808, ENST00000811809, ENST00000811810, ENST00000811811, ENST00000811812, ENST00000811813, ENST00000811814, ENST00000811815, ENST00000811816, ENST00000811817, ENST00000811818, ENST00000811819, ENST00000811820, ENST00000811821, ENST00000811822, ENST00000811823, ENST00000811824, ENST00000811825, ENST00000811826, ENST00000811827, ENST00000811828, ENST00000811829, ENST00000811830, ENST00000811831, ENST00000811832, ENST00000811833, ENST00000811834, ENST00000811835, ENST00000811836, ENST00000811837, ENST00000811838, ENST00000811839, ENST00000811840, ENST00000811841, ENST00000811842, ENST00000811843, ENST00000811844, ENST00000811845, ENST00000811846, ENST00000811847

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000462492 — 3 exons

Exon	Start	End
ENSE00001850577	72099904	72100010
ENSE00003982476	72092267	72092474
ENSE00004210123	72100788	72100987

Expression profiles

Bgee: expression breadth ubiquitous, 160 present calls, max score 90.47.

FANTOM5 (CAGE): breadth broad, TPM avg 3.3955 / max 567.6905, expressed in 344 samples.

FANTOM5 promoters (12 alternative TSS)

Promoter ID	TPM avg	Samples expressed
43130	1.0612	177
43128	1.0009	101
43124	0.2821	70
43131	0.2025	94
43127	0.1657	61
43129	0.1652	74
43123	0.1264	30
43125	0.1191	54
43126	0.1094	51
43134	0.0805	45

Top tissues by expression

240 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
monocyte	CL:0000576	90.47	gold quality
leukocyte	CL:0000738	90.17	gold quality
granulocyte	CL:0000094	89.11	gold quality
bone marrow cell	CL:0002092	82.92	gold quality
vermiform appendix	UBERON:0001154	78.85	gold quality
blood	UBERON:0000178	78.09	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	77.34	gold quality
colonic epithelium	UBERON:0000397	76.82	gold quality
spinal cord	UBERON:0002240	74.00	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	72.45	silver quality
lymph node	UBERON:0000029	70.82	gold quality
islet of Langerhans	UBERON:0000006	70.80	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	70.62	gold quality
caecum	UBERON:0001153	70.58	gold quality
corpus callosum	UBERON:0002336	69.72	gold quality
ventricular zone	UBERON:0003053	69.48	gold quality
spleen	UBERON:0002106	69.06	gold quality
ganglionic eminence	UBERON:0004023	68.88	gold quality
hypothalamus	UBERON:0001898	68.71	gold quality
amygdala	UBERON:0001876	68.24	gold quality
left testis	UBERON:0004533	67.61	gold quality
putamen	UBERON:0001874	67.18	gold quality
sperm	CL:0000019	66.97	silver quality
right testis	UBERON:0004534	66.84	gold quality
tonsil	UBERON:0002372	66.44	gold quality
stromal cell of endometrium	CL:0002255	65.98	gold quality
testis	UBERON:0000473	65.43	gold quality
substantia nigra	UBERON:0002038	64.65	gold quality
smooth muscle tissue	UBERON:0001135	64.21	gold quality
caudate nucleus	UBERON:0001873	63.96	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.65

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.