LINC00882

Summary

LINC00882 (long intergenic non-protein coding RNA 882, HGNC:48568) is a long non-coding RNA gene on chromosome 3q13.12.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:48568
Approved symbol	LINC00882
Name	long intergenic non-protein coding RNA 882
Location	3q13.12
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000242759
Ensembl biotype	lncRNA
Entrez	100302640
RNAcentral	URS000075B77A — lncRNA, 615 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 77 — 77 lncRNA

ENST00000473636, ENST00000477210, ENST00000479612, ENST00000484698, ENST00000606742, ENST00000607542, ENST00000607801, ENST00000652783, ENST00000653044, ENST00000654704, ENST00000654920, ENST00000655451, ENST00000655832, ENST00000656235, ENST00000656342, ENST00000656555, ENST00000656816, ENST00000656835, ENST00000657720, ENST00000657806, ENST00000657909, ENST00000658706, ENST00000658897, ENST00000658929, ENST00000658978, ENST00000659129, ENST00000659317, ENST00000659503, ENST00000659605, ENST00000659654, ENST00000659809, ENST00000659859, ENST00000660263, ENST00000660310, ENST00000660353, ENST00000660515, ENST00000660636, ENST00000660757, ENST00000660862, ENST00000661400, ENST00000661735, ENST00000662123, ENST00000662368, ENST00000662455, ENST00000662816, ENST00000662886, ENST00000663024, ENST00000664169, ENST00000664426, ENST00000664588, ENST00000665402, ENST00000665806, ENST00000666382, ENST00000666429, ENST00000666600, ENST00000666687, ENST00000667805, ENST00000667861, ENST00000667876, ENST00000667931, ENST00000668464, ENST00000668760, ENST00000668928, ENST00000668963, ENST00000669116, ENST00000669363, ENST00000669624, ENST00000669797, ENST00000669895, ENST00000669924, ENST00000670214, ENST00000671205, ENST00000671373, ENST00000671604, ENST00000671678, ENST00000671682, ENST00000702844

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000473636 — 4 exons

Exon	Start	End
ENSE00001840387	107129193	107129317
ENSE00001853860	107111409	107112146
ENSE00001938302	107240443	107240652
ENSE00001947097	107129888	107129992

Expression profiles

Bgee: expression breadth ubiquitous, 158 present calls, max score 87.58.

FANTOM5 (CAGE): breadth broad, TPM avg 2.9882 / max 113.3211, expressed in 758 samples.

FANTOM5 promoters (8 alternative TSS)

Promoter ID	TPM avg	Samples expressed
43629	2.6710	699
43624	0.1118	32
43625	0.1115	48
43628	0.0297	9
43627	0.0243	4
43626	0.0234	8
43619	0.0134	3
43623	0.0031	1

Top tissues by expression

246 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	87.58	gold quality
left testis	UBERON:0004533	87.43	gold quality
right testis	UBERON:0004534	87.15	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	85.11	gold quality
testis	UBERON:0000473	84.39	gold quality
sural nerve	UBERON:0015488	83.60	gold quality
Brodmann (1909) area 9	UBERON:0013540	82.27	gold quality
hindlimb stylopod muscle	UBERON:0004252	82.03	gold quality
prefrontal cortex	UBERON:0000451	81.97	gold quality
anterior cingulate cortex	UBERON:0009835	81.94	gold quality
right frontal lobe	UBERON:0002810	81.30	gold quality
right uterine tube	UBERON:0001302	81.11	gold quality
spinal cord	UBERON:0002240	81.08	gold quality
nucleus accumbens	UBERON:0001882	80.75	gold quality
putamen	UBERON:0001874	80.49	gold quality
apex of heart	UBERON:0002098	80.06	gold quality
amygdala	UBERON:0001876	79.29	gold quality
heart left ventricle	UBERON:0002084	79.25	gold quality
calcaneal tendon	UBERON:0003701	79.09	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	78.91	gold quality
caudate nucleus	UBERON:0001873	78.90	gold quality
hypothalamus	UBERON:0001898	78.46	gold quality
left ovary	UBERON:0002119	78.40	gold quality
cardiac ventricle	UBERON:0002082	77.94	gold quality
right atrium auricular region	UBERON:0006631	77.74	gold quality
cardiac atrium	UBERON:0002081	76.79	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	76.71	gold quality
heart	UBERON:0000948	76.11	gold quality
right ovary	UBERON:0002118	76.11	gold quality
adenohypophysis	UBERON:0002196	75.76	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	4.88

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 2)

• LINC00882 promotes platelet-derived growth factor-induced cell proliferation of airway smooth muscle cells by enhancing Wnt/beta-catenin signaling via sponging miR-3619-5p, suggesting a potential role for LINC00882 in airway remodeling in pediatric asthma. (PMID:31014672)
• LINC00882 Plays a Tumor-promoter Role in Colorectal Cancer by Targeting miR-3619-5p to Up-regulate CTNNB1. (PMID:34399990)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.