LINC00891

Summary

LINC00891 (long intergenic non-protein coding RNA 891, HGNC:48577) is a long non-coding RNA gene on chromosome Xq13.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:48577
Approved symbol	LINC00891
Name	long intergenic non-protein coding RNA 891
Location	Xq13.1
Locus type	RNA, long non-coding
Status	Approved
Aliases	FLJ46446
Ensembl gene	ENSG00000281852
Ensembl biotype	lncRNA
Entrez	441501
RNAcentral	URS000075B2AA — lncRNA, 1064 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 8 — 8 lncRNA

ENST00000627173, ENST00000792348, ENST00000792349, ENST00000792350, ENST00000792351, ENST00000792352, ENST00000792353, ENST00000792354

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000627173 — 3 exons

Exon	Start	End
ENSE00003769880	71700821	71701043
ENSE00004174246	71702672	71706455
ENSE00004174249	71697088	71697301

Expression profiles

Bgee: expression breadth ubiquitous, 129 present calls, max score 95.63.

Top tissues by expression

131 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
thymus	UBERON:0002370	95.63	gold quality
smooth muscle tissue	UBERON:0001135	77.19	gold quality
left uterine tube	UBERON:0001303	76.24	gold quality
myometrium	UBERON:0001296	75.13	gold quality
body of uterus	UBERON:0009853	75.10	gold quality
urinary bladder	UBERON:0001255	73.95	gold quality
calcaneal tendon	UBERON:0003701	73.18	gold quality
ovary	UBERON:0000992	72.94	gold quality
left ovary	UBERON:0002119	72.63	gold quality
fallopian tube	UBERON:0003889	72.02	gold quality
right ovary	UBERON:0002118	71.79	gold quality
muscle layer of sigmoid colon	UBERON:0035805	71.37	gold quality
colonic epithelium	UBERON:0000397	70.03	silver quality
rectum	UBERON:0001052	69.68	gold quality
right lung	UBERON:0002167	69.60	gold quality
quadriceps femoris	UBERON:0001377	69.42	gold quality
upper lobe of left lung	UBERON:0008952	68.96	gold quality
lung	UBERON:0002048	68.66	gold quality
lymph node	UBERON:0000029	68.05	gold quality
cerebellar vermis	UBERON:0004720	67.75	gold quality
vermiform appendix	UBERON:0001154	67.02	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	66.64	gold quality
bone marrow cell	CL:0002092	66.55	silver quality
tibial nerve	UBERON:0001323	66.04	gold quality
colon	UBERON:0001155	65.92	gold quality
duodenum	UBERON:0002114	65.20	gold quality
lower esophagus muscularis layer	UBERON:0035833	64.87	gold quality
lower esophagus	UBERON:0013473	64.81	gold quality
muscle tissue	UBERON:0002385	64.75	gold quality
tonsil	UBERON:0002372	64.65	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	2.98

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• LINC00891 Attenuates the Proliferation and Metastasis of Osteosarcoma Cells via miR-27a-3p/TET1 Axis. (PMID:37643326)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.