LINC00899

Summary

LINC00899 (long intergenic non-protein coding RNA 899, HGNC:48583) is a long non-coding RNA gene on chromosome 22q13.31.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:48583
Approved symbol	LINC00899
Name	long intergenic non-protein coding RNA 899
Location	22q13.31
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000231711
Ensembl biotype	lncRNA
Entrez	100271722
RNAcentral	URS000075B967 — lncRNA, 1625 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 9 — 7 lncRNA, 2 retained_intron

ENST00000421538, ENST00000444890, ENST00000609737, ENST00000692935, ENST00000717660, ENST00000717661, ENST00000717662, ENST00000717663, ENST00000717664

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000421538 — 3 exons

Exon	Start	End
ENSE00001594580	46042574	46043699
ENSE00001611194	46040266	46041052
ENSE00001637895	46043940	46044610

Expression profiles

Bgee: expression breadth ubiquitous, 195 present calls, max score 84.84.

Top tissues by expression

242 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
buccal mucosa cell	CL:0002336	84.84	gold quality
left ovary	UBERON:0002119	82.65	gold quality
body of uterus	UBERON:0009853	81.76	gold quality
sural nerve	UBERON:0015488	81.40	gold quality
endocervix	UBERON:0000458	80.41	gold quality
right uterine tube	UBERON:0001302	80.31	gold quality
right ovary	UBERON:0002118	79.95	gold quality
ovary	UBERON:0000992	78.74	gold quality
tibial nerve	UBERON:0001323	78.74	gold quality
lower esophagus muscularis layer	UBERON:0035833	78.58	gold quality
lower esophagus	UBERON:0013473	78.54	gold quality
popliteal artery	UBERON:0002250	78.44	gold quality
tibial artery	UBERON:0007610	78.42	gold quality
muscle layer of sigmoid colon	UBERON:0035805	78.19	gold quality
descending thoracic aorta	UBERON:0002345	77.74	gold quality
aorta	UBERON:0000947	77.64	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	77.43	gold quality
left coronary artery	UBERON:0001626	77.35	gold quality
left uterine tube	UBERON:0001303	77.15	gold quality
ascending aorta	UBERON:0001496	76.88	gold quality
ectocervix	UBERON:0012249	76.85	gold quality
thoracic aorta	UBERON:0001515	76.81	gold quality
monocyte	CL:0000576	76.80	gold quality
coronary artery	UBERON:0001621	76.48	gold quality
leukocyte	CL:0000738	76.05	gold quality
uterine cervix	UBERON:0000002	75.90	gold quality
right coronary artery	UBERON:0001625	75.86	gold quality
right lung	UBERON:0002167	75.53	gold quality
hindlimb stylopod muscle	UBERON:0004252	75.36	gold quality
gastrocnemius	UBERON:0001388	75.32	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.90

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 2)

• serum LINC00899 expression level was significantly reduced when the patients achieved complete remission (PMID:30468482)
• Long Noncoding RNA LINC00899/miR-944/ESR1 Axis Regulates Cervical Cancer Cell Proliferation, Migration, and Invasion. (PMID:34161168)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.