LINC00900

Summary

LINC00900 (long intergenic non-protein coding RNA 900, HGNC:27444) is a long non-coding RNA gene on chromosome 11q23.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:27444
Approved symbol	LINC00900
Name	long intergenic non-protein coding RNA 900
Location	11q23.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000246100
Ensembl biotype	lncRNA
Entrez	283143
RNAcentral	URS000075BB5B — lncRNA, 2256 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 18 — 18 lncRNA

ENST00000499809, ENST00000501294, ENST00000514294, ENST00000535683, ENST00000537070, ENST00000602803, ENST00000653265, ENST00000654271, ENST00000657395, ENST00000666130, ENST00000690724, ENST00000763705, ENST00000763706, ENST00000763707, ENST00000763708, ENST00000763709, ENST00000763710, ENST00000763711

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000499809 — 3 exons

Exon	Start	End
ENSE00001970998	115754248	115757292
ENSE00001980807	115760030	115760194
ENSE00001987029	115758141	115758252

Expression profiles

Bgee: expression breadth ubiquitous, 153 present calls, max score 72.74.

FANTOM5 (CAGE): breadth broad, TPM avg 0.6631 / max 20.1825, expressed in 356 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
122410	0.5042	280
122409	0.1267	49
122411	0.0322	7

Top tissues by expression

242 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
islet of Langerhans	UBERON:0000006	72.74	gold quality
cerebellar hemisphere	UBERON:0002245	71.08	gold quality
cerebellar cortex	UBERON:0002129	70.93	gold quality
right hemisphere of cerebellum	UBERON:0014890	70.75	gold quality
colonic epithelium	UBERON:0000397	70.45	silver quality
buccal mucosa cell	CL:0002336	69.71	silver quality
nucleus accumbens	UBERON:0001882	69.08	gold quality
cerebellum	UBERON:0002037	68.88	gold quality
calcaneal tendon	UBERON:0003701	68.70	gold quality
anterior cingulate cortex	UBERON:0009835	68.31	gold quality
pancreatic ductal cell	CL:0002079	67.85	silver quality
right frontal lobe	UBERON:0002810	67.72	gold quality
prefrontal cortex	UBERON:0000451	67.58	gold quality
right adrenal gland cortex	UBERON:0035827	67.43	gold quality
Brodmann (1909) area 9	UBERON:0013540	67.28	gold quality
upper arm skin	UBERON:0004263	67.20	gold quality
monocyte	CL:0000576	66.63	gold quality
caudate nucleus	UBERON:0001873	66.51	gold quality
skin of abdomen	UBERON:0001416	66.45	gold quality
left adrenal gland cortex	UBERON:0035825	66.33	gold quality
skin of leg	UBERON:0001511	66.32	gold quality
ventricular zone	UBERON:0003053	66.29	gold quality
left adrenal gland	UBERON:0001234	66.28	gold quality
right adrenal gland	UBERON:0001233	66.13	gold quality
ileal mucosa	UBERON:0000331	65.92	silver quality
putamen	UBERON:0001874	65.92	gold quality
tibialis anterior	UBERON:0001385	65.91	silver quality
zone of skin	UBERON:0000014	65.63	gold quality
amygdala	UBERON:0001876	65.28	gold quality
vermiform appendix	UBERON:0001154	64.82	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	3.38

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 2)

• Down-regulation of SLC16A-AS1 and LINC00900 lncRNAs in Iranian patients with breast cancer. (PMID:36641651)
• YTHDF1 promotes the viability and self-renewal of glioma stem cells by enhancing LINC00900 stability. (PMID:38551160)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.