LINC00926

Summary

LINC00926 (long intergenic non-protein coding RNA 926, HGNC:27514) is a long non-coding RNA gene on chromosome 15q21.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:27514
Approved symbol	LINC00926
Name	long intergenic non-protein coding RNA 926
Location	15q21.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000247982
Ensembl biotype	lncRNA
Entrez	283663
RNAcentral	URS000075D34B — lncRNA, 2534 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 14 — 14 lncRNA

ENST00000501726, ENST00000502027, ENST00000613170, ENST00000620766, ENST00000793587, ENST00000793588, ENST00000793589, ENST00000793590, ENST00000793591, ENST00000793592, ENST00000793593, ENST00000793594, ENST00000793595, ENST00000793596

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000501726 — 3 exons

Exon	Start	End
ENSE00001971494	57307542	57307769
ENSE00001981262	57300365	57300924
ENSE00001988394	57305319	57307068

Expression profiles

Bgee: expression breadth ubiquitous, 223 present calls, max score 96.63.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.1549 / max 27.1227, expressed in 37 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
146839	0.1160	26
146840	0.0209	13
146841	0.0180	5

Top tissues by expression

245 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
spleen	UBERON:0002106	96.63	gold quality
lymph node	UBERON:0000029	95.37	gold quality
kidney epithelium	UBERON:0004819	95.37	silver quality
granulocyte	CL:0000094	94.80	gold quality
vermiform appendix	UBERON:0001154	94.79	gold quality
upper arm skin	UBERON:0004263	92.95	silver quality
caecum	UBERON:0001153	92.73	gold quality
cardiac muscle of right atrium	UBERON:0003379	89.14	gold quality
blood	UBERON:0000178	89.06	gold quality
left ventricle myocardium	UBERON:0006566	88.96	gold quality
nasal cavity epithelium	UBERON:0005384	87.91	gold quality
epithelial cell of pancreas	CL:0000083	87.89	gold quality
small intestine Peyer’s patch	UBERON:0003454	87.61	gold quality
vena cava	UBERON:0004087	85.07	silver quality
tonsil	UBERON:0002372	84.53	gold quality
small intestine	UBERON:0002108	84.38	gold quality
superficial temporal artery	UBERON:0001614	84.08	gold quality
ileal mucosa	UBERON:0000331	82.89	gold quality
body of tongue	UBERON:0011876	82.51	silver quality
tongue	UBERON:0001723	82.32	silver quality
superior surface of tongue	UBERON:0007371	82.29	gold quality
epithelium of nasopharynx	UBERON:0001951	82.18	gold quality
cardia of stomach	UBERON:0001162	81.83	gold quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	81.71	silver quality
subthalamic nucleus	UBERON:0001906	81.64	gold quality
bone marrow	UBERON:0002371	81.45	gold quality
vastus lateralis	UBERON:0001379	81.32	gold quality
pylorus	UBERON:0001166	81.18	silver quality
dorsal plus ventral thalamus	UBERON:0001897	81.17	silver quality
ventral tegmental area	UBERON:0002691	81.17	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	21.71

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 5)

• FOXO3A-induced LINC00926 suppresses breast tumor growth and metastasis through inhibition of PGK1-mediated Warburg effect. (PMID:33940159)
• Long non-coding RNA LINC00926 regulates WNT10B signaling pathway thereby altering inflammatory gene expression in PTSD. (PMID:35551428)
• LINC00926 is involved in hypoxia-induced vascular endothelial cell dysfunction via miR-3194-5p regulating JAK1/STAT3 signaling pathway. (PMID:36647631)
• [LINC00926 promotes pyroptosis of hypoxia-induced human umbilical vein vascular endothelial cells by recruiting ELAVL1]. (PMID:37313823)
• LINC00926 promotes progression of renal cell carcinoma via regulating miR-30a-5p/SOX4 axis and activating IFNgamma-JAK2-STAT1 pathway. (PMID:37866544)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.