LINC00937

Summary

LINC00937 (long intergenic non-protein coding RNA 937, HGNC:48629) is a long non-coding RNA gene on chromosome 12p13.31.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:48629
Approved symbol	LINC00937
Name	long intergenic non-protein coding RNA 937
Location	12p13.31
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000226091
Ensembl biotype	lncRNA
Entrez	389634
RNAcentral	URS000075A8FE — lncRNA, 682 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 96 — 96 lncRNA

ENST00000420040, ENST00000536539, ENST00000536560, ENST00000537659, ENST00000538304, ENST00000539348, ENST00000544461, ENST00000656887, ENST00000693495, ENST00000734927, ENST00000734928, ENST00000734929, ENST00000734930, ENST00000734931, ENST00000734932, ENST00000734933, ENST00000734934, ENST00000734935, ENST00000734936, ENST00000734937, ENST00000734938, ENST00000734939, ENST00000734940, ENST00000734941, ENST00000734942, ENST00000734943, ENST00000734944, ENST00000734945, ENST00000734946, ENST00000734947, ENST00000734948, ENST00000734949, ENST00000734950, ENST00000734951, ENST00000734952, ENST00000734953, ENST00000734954, ENST00000734955, ENST00000734956, ENST00000734957, ENST00000734958, ENST00000734959, ENST00000734960, ENST00000734961, ENST00000734962, ENST00000734963, ENST00000734964, ENST00000734965, ENST00000734966, ENST00000734967, ENST00000734968, ENST00000734969, ENST00000734970, ENST00000734971, ENST00000734972, ENST00000734973, ENST00000734974, ENST00000734975, ENST00000734976, ENST00000734977, ENST00000734978, ENST00000734979, ENST00000734980, ENST00000734981, ENST00000734982, ENST00000734983, ENST00000734984, ENST00000734985, ENST00000734986, ENST00000734987, ENST00000734988, ENST00000734989, ENST00000734990, ENST00000734991, ENST00000734992, ENST00000734993, ENST00000734994, ENST00000734995, ENST00000734996, ENST00000734997, ENST00000734998, ENST00000734999, ENST00000735000, ENST00000735001, ENST00000735002, ENST00000735003, ENST00000735004, ENST00000735005, ENST00000735006, ENST00000735007, ENST00000735008, ENST00000735009, ENST00000735010, ENST00000735011, ENST00000735012, ENST00000735013

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000420040 — 2 exons

Exon	Start	End
ENSE00002215303	8390270	8390752
ENSE00002312564	8356963	8357141

Expression profiles

Bgee: expression breadth ubiquitous, 184 present calls, max score 97.13.

Top tissues by expression

232 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right uterine tube	UBERON:0001302	97.13	gold quality
buccal mucosa cell	CL:0002336	95.33	gold quality
monocyte	CL:0000576	90.67	gold quality
leukocyte	CL:0000738	89.47	gold quality
tendon of biceps brachii	UBERON:0008188	88.67	gold quality
granulocyte	CL:0000094	86.41	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	85.25	gold quality
jejunal mucosa	UBERON:0000399	83.52	gold quality
blood	UBERON:0000178	82.55	gold quality
bone marrow cell	CL:0002092	81.42	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	80.64	gold quality
medial globus pallidus	UBERON:0002477	80.32	gold quality
globus pallidus	UBERON:0001875	78.47	gold quality
spleen	UBERON:0002106	78.22	gold quality
corpus callosum	UBERON:0002336	77.49	gold quality
renal medulla	UBERON:0000362	77.45	gold quality
jejunum	UBERON:0002115	76.38	gold quality
endocervix	UBERON:0000458	76.27	gold quality
cerebellar vermis	UBERON:0004720	76.18	gold quality
vermiform appendix	UBERON:0001154	75.96	gold quality
caecum	UBERON:0001153	75.50	gold quality
nipple	UBERON:0002030	74.35	silver quality
left uterine tube	UBERON:0001303	73.48	gold quality
cardia of stomach	UBERON:0001162	73.09	silver quality
right lung	UBERON:0002167	72.96	gold quality
cortex of kidney	UBERON:0001225	72.72	gold quality
cerebellar cortex	UBERON:0002129	72.54	gold quality
tendon	UBERON:0000043	72.50	gold quality
cerebellar hemisphere	UBERON:0002245	72.48	gold quality
right hemisphere of cerebellum	UBERON:0014890	72.32	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	5.07

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• LINC00937 suppresses keloid fibroblast proliferation and extracellular matrix deposition by targeting the miR-28-5p/MC1R axis. (PMID:34486677)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.