LINC00944

Summary

LINC00944 (long intergenic non-protein coding RNA 944, HGNC:48640) is a long non-coding RNA gene on chromosome 12q24.32.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:48640
Approved symbol	LINC00944
Name	long intergenic non-protein coding RNA 944
Location	12q24.32
Locus type	RNA, long non-coding
Status	Approved
Aliases	DMDRMR
Ensembl gene	ENSG00000256128
Ensembl biotype	lncRNA
Entrez	387895
RNAcentral	URS000075AEB0 — lncRNA, 621 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 119 — 119 lncRNA

ENST00000536517, ENST00000537478, ENST00000540684, ENST00000540814, ENST00000541065, ENST00000541769, ENST00000542248, ENST00000544499, ENST00000545508, ENST00000545853, ENST00000546117, ENST00000654541, ENST00000655370, ENST00000656536, ENST00000656909, ENST00000659004, ENST00000659581, ENST00000660736, ENST00000661743, ENST00000662540, ENST00000664274, ENST00000665130, ENST00000665131, ENST00000665986, ENST00000666903, ENST00000670633, ENST00000671627, ENST00000689745, ENST00000693472, ENST00000809141, ENST00000809142, ENST00000809143, ENST00000809144, ENST00000809145, ENST00000809146, ENST00000809147, ENST00000809148, ENST00000809149, ENST00000809150, ENST00000809151, ENST00000809152, ENST00000809153, ENST00000809154, ENST00000809155, ENST00000809156, ENST00000809157, ENST00000809158, ENST00000809159, ENST00000809160, ENST00000809161, ENST00000809162, ENST00000809163, ENST00000809164, ENST00000809165, ENST00000809166, ENST00000809167, ENST00000809168, ENST00000809169, ENST00000809170, ENST00000809171, ENST00000809172, ENST00000809173, ENST00000809174, ENST00000809175, ENST00000809176, ENST00000809177, ENST00000809178, ENST00000809179, ENST00000809180, ENST00000809181, ENST00000809182, ENST00000809183, ENST00000809184, ENST00000809185, ENST00000809186, ENST00000809187, ENST00000809188, ENST00000809189, ENST00000809190, ENST00000809191, ENST00000809192, ENST00000809193, ENST00000809194, ENST00000809195, ENST00000809196, ENST00000809197, ENST00000809198, ENST00000809199, ENST00000809200, ENST00000809201, ENST00000809202, ENST00000809203, ENST00000809204, ENST00000809205, ENST00000809206, ENST00000809207, ENST00000809208, ENST00000809209, ENST00000809210, ENST00000809211, ENST00000809212, ENST00000809213, ENST00000809214, ENST00000809215, ENST00000809216, ENST00000809424, ENST00000809425, ENST00000809426, ENST00000809427, ENST00000809428, ENST00000809429, ENST00000809430, ENST00000809431, ENST00000809432, ENST00000809433, ENST00000809434, ENST00000809435, ENST00000809436, ENST00000809538

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000536517 — 3 exons

Exon	Start	End
ENSE00002306426	126760932	126761057
ENSE00004204739	126752090	126752451
ENSE00004204763	126772079	126772336

Expression profiles

Bgee: expression breadth ubiquitous, 165 present calls, max score 89.41.

FANTOM5 (CAGE): breadth broad, TPM avg 0.7049 / max 31.9650, expressed in 272 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
134079	0.5167	223
134080	0.1188	70
134081	0.0694	31

Top tissues by expression

230 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
left testis	UBERON:0004533	89.41	gold quality
right testis	UBERON:0004534	89.01	gold quality
epithelium of nasopharynx	UBERON:0001951	86.58	silver quality
testis	UBERON:0000473	85.64	gold quality
sperm	CL:0000019	85.56	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.90	gold quality
granulocyte	CL:0000094	81.84	gold quality
superficial temporal artery	UBERON:0001614	81.53	gold quality
bone marrow cell	CL:0002092	78.36	gold quality
mucosa of paranasal sinus	UBERON:0005030	75.59	gold quality
gingival epithelium	UBERON:0001949	75.51	silver quality
ventricular zone	UBERON:0003053	73.33	gold quality
ganglionic eminence	UBERON:0004023	71.85	gold quality
vermiform appendix	UBERON:0001154	70.13	gold quality
lymph node	UBERON:0000029	69.55	gold quality
spleen	UBERON:0002106	69.27	gold quality
tonsil	UBERON:0002372	68.53	gold quality
colonic epithelium	UBERON:0000397	67.17	silver quality
small intestine Peyer’s patch	UBERON:0003454	65.61	gold quality
bone marrow	UBERON:0002371	65.39	gold quality
caecum	UBERON:0001153	65.36	gold quality
trabecular bone tissue	UBERON:0002483	64.91	silver quality
small intestine	UBERON:0002108	64.10	gold quality
blood	UBERON:0000178	63.97	gold quality
rectum	UBERON:0001052	63.96	gold quality
cortical plate	UBERON:0005343	63.72	gold quality
oocyte	CL:0000023	63.67	gold quality
trachea	UBERON:0003126	63.36	silver quality
lower lobe of lung	UBERON:0008949	62.12	silver quality
leukocyte	CL:0000738	60.66	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.25

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 2)

• Immune-related IncRNA LINC00944 responds to variations in ADAR1 levels and it is associated with breast cancer prognosis. (PMID:33383047)
• A genome-wide association study identifies novel association between genetic variants in GGT7 and LINC00944 and hypertension. (PMID:34047475)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.