LINC00945

Summary

LINC00945 (long intergenic non-protein coding RNA 945, HGNC:48643) is a long non-coding RNA gene on chromosome 21q22.11.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:48643
Approved symbol	LINC00945
Name	long intergenic non-protein coding RNA 945
Location	21q22.11
Locus type	RNA, long non-coding
Status	Approved
Aliases	TCONS_00028834
Ensembl gene	ENSG00000232539
Ensembl biotype	lncRNA
Entrez	101930746
RNAcentral	URS000075C033 — lncRNA, 849 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000453716, ENST00000777848

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000453716 — 5 exons

Exon	Start	End
ENSE00001607713	33062792	33062816
ENSE00001625299	33064603	33064983
ENSE00001663506	33064276	33064448
ENSE00001670124	33057829	33057898
ENSE00001733942	33058101	33058204

Expression profiles

Bgee: expression breadth broad, 46 present calls, max score 57.60.

Top tissues by expression

46 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
monocyte	CL:0000576	57.60	gold quality
blood	UBERON:0000178	55.52	gold quality
prefrontal cortex	UBERON:0000451	53.94	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	53.49	gold quality
esophagus mucosa	UBERON:0002469	52.37	gold quality
cortex of kidney	UBERON:0001225	50.48	silver quality
frontal cortex	UBERON:0001870	49.87	gold quality
corpus callosum	UBERON:0002336	49.46	silver quality
primary visual cortex	UBERON:0002436	49.33	silver quality
olfactory segment of nasal mucosa	UBERON:0005386	49.16	gold quality
bone marrow	UBERON:0002371	49.04	silver quality
islet of Langerhans	UBERON:0000006	48.85	gold quality
putamen	UBERON:0001874	48.74	gold quality
substantia nigra	UBERON:0002038	48.10	gold quality
muscle of leg	UBERON:0001383	48.09	silver quality
Brodmann (1909) area 9	UBERON:0013540	47.59	gold quality
kidney	UBERON:0002113	47.11	silver quality
cerebral cortex	UBERON:0000956	47.01	gold quality
amygdala	UBERON:0001876	46.95	gold quality
brain	UBERON:0000955	46.70	gold quality
gastrocnemius	UBERON:0001388	46.30	silver quality
Ammon’s horn	UBERON:0001954	46.09	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	45.81	gold quality
superior frontal gyrus	UBERON:0002661	45.65	silver quality
caudate nucleus	UBERON:0001873	45.01	gold quality
nucleus accumbens	UBERON:0001882	44.97	gold quality
hypothalamus	UBERON:0001898	44.81	gold quality
adult mammalian kidney	UBERON:0000082	44.52	silver quality
right frontal lobe	UBERON:0002810	44.48	gold quality
omental fat pad	UBERON:0010414	43.65	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.81

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.