LINC00955

Summary

LINC00955 (long intergenic non-protein coding RNA 955, HGNC:26644) is a long non-coding RNA gene on chromosome 4p16.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:26644
Approved symbol	LINC00955
Name	long intergenic non-protein coding RNA 955
Location	4p16.3
Locus type	RNA, long non-coding
Status	Approved
Aliases	FLJ35424
Ensembl gene	ENSG00000216560
Ensembl biotype	lncRNA
Entrez	285492
RNAcentral	URS000075B50D — lncRNA, 2483 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 11 — 10 lncRNA, 1 retained_intron

ENST00000502775, ENST00000514422, ENST00000826270, ENST00000826271, ENST00000826272, ENST00000826273, ENST00000826274, ENST00000826275, ENST00000826276, ENST00000826277, ENST00000826278

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000502775 — 4 exons

Exon	Start	End
ENSE00002030862	3588934	3589014
ENSE00002042201	3590264	3590711
ENSE00002050227	3576934	3577123
ENSE00002070288	3588051	3588187

Expression profiles

Bgee: expression breadth broad, 51 present calls, max score 94.90.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.0141 / max 10.8693, expressed in 6 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
46719	0.0103	6
46718	0.0037	3

Top tissues by expression

163 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	94.90	gold quality
jejunal mucosa	UBERON:0000399	82.13	gold quality
small intestine Peyer’s patch	UBERON:0003454	78.76	gold quality
small intestine	UBERON:0002108	77.37	gold quality
duodenum	UBERON:0002114	73.40	gold quality
adult mammalian kidney	UBERON:0000082	68.19	gold quality
transverse colon	UBERON:0001157	66.65	gold quality
intestine	UBERON:0000160	64.91	gold quality
jejunum	UBERON:0002115	63.42	gold quality
rectum	UBERON:0001052	59.60	gold quality
kidney	UBERON:0002113	59.44	gold quality
metanephros cortex	UBERON:0010533	59.23	gold quality
colon	UBERON:0001155	58.80	gold quality
cortex of kidney	UBERON:0001225	58.11	gold quality
large intestine	UBERON:0000059	57.64	gold quality
cortical plate	UBERON:0005343	57.05	gold quality
muscle layer of sigmoid colon	UBERON:0035805	52.47	gold quality
metanephros	UBERON:0000081	51.88	gold quality
endothelial cell	CL:0000115	51.56	gold quality
monocyte	CL:0000576	51.21	silver quality
prefrontal cortex	UBERON:0000451	49.17	silver quality
body of uterus	UBERON:0009853	49.11	gold quality
lower esophagus muscularis layer	UBERON:0035833	48.93	gold quality
gastrocnemius	UBERON:0001388	46.65	silver quality
vermiform appendix	UBERON:0001154	46.52	gold quality
skin of leg	UBERON:0001511	46.27	silver quality
anatomical system	UBERON:0000467	44.86	gold quality
multicellular organism	UBERON:0000468	44.59	gold quality
material anatomical entity	UBERON:0000465	44.56	gold quality
cerebellar hemisphere	UBERON:0002245	43.89	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.95

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• LINC00955 suppresses colorectal cancer growth by acting as a molecular scaffold of TRIM25 and Sp1 to Inhibit DNMT3B-mediated methylation of the PHIP promoter. (PMID:37742010)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.