LINC00960

Summary

LINC00960 (long intergenic non-protein coding RNA 960, HGNC:48710) is a long non-coding RNA gene on chromosome 3p12.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:48710
Approved symbol	LINC00960
Name	long intergenic non-protein coding RNA 960
Location	3p12.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000242516
Ensembl biotype	lncRNA
Entrez	401074
RNAcentral	URS000043E1DD — lncRNA, 1333 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 13 — 13 lncRNA

ENST00000463183, ENST00000492922, ENST00000656252, ENST00000657028, ENST00000662338, ENST00000665741, ENST00000666754, ENST00000668145, ENST00000669013, ENST00000692722, ENST00000810062, ENST00000810063, ENST00000810064

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000463183 — 6 exons

Exon	Start	End
ENSE00001813321	75678833	75679314
ENSE00001855169	75675764	75675880
ENSE00001886760	75673194	75673238
ENSE00001898357	75675968	75676128
ENSE00001914299	75673847	75674006
ENSE00001937471	75672391	75672769

Expression profiles

Bgee: expression breadth ubiquitous, 175 present calls, max score 87.65.

FANTOM5 (CAGE): breadth broad, TPM avg 1.1362 / max 28.5508, expressed in 647 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
37345	0.7538	481
37346	0.3824	241

Top tissues by expression

240 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
lower esophagus mucosa	UBERON:0035834	87.65	gold quality
sperm	CL:0000019	86.31	gold quality
mucosa of transverse colon	UBERON:0004991	83.83	gold quality
stromal cell of endometrium	CL:0002255	82.62	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	81.94	gold quality
body of pancreas	UBERON:0001150	80.69	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	79.69	gold quality
right coronary artery	UBERON:0001625	78.79	gold quality
esophagus mucosa	UBERON:0002469	78.44	gold quality
ectocervix	UBERON:0012249	77.52	gold quality
colonic epithelium	UBERON:0000397	76.69	gold quality
pancreas	UBERON:0001264	76.48	gold quality
vagina	UBERON:0000996	76.24	gold quality
endocervix	UBERON:0000458	75.96	gold quality
right lung	UBERON:0002167	74.94	gold quality
skin of abdomen	UBERON:0001416	74.52	gold quality
left coronary artery	UBERON:0001626	74.42	gold quality
cortical plate	UBERON:0005343	74.21	gold quality
thoracic aorta	UBERON:0001515	73.86	gold quality
ascending aorta	UBERON:0001496	73.73	gold quality
esophagus	UBERON:0001043	73.71	gold quality
left lobe of thyroid gland	UBERON:0001120	73.41	gold quality
mucosa of stomach	UBERON:0001199	72.94	gold quality
coronary artery	UBERON:0001621	72.92	gold quality
minor salivary gland	UBERON:0001830	72.86	gold quality
omental fat pad	UBERON:0010414	72.86	gold quality
peritoneum	UBERON:0002358	72.77	gold quality
gall bladder	UBERON:0002110	72.71	gold quality
left ovary	UBERON:0002119	72.68	gold quality
uterine cervix	UBERON:0000002	72.58	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	5.10

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 4)

• Exosome-Derived LINC00960 and LINC02470 Promote the Epithelial-Mesenchymal Transition and Aggressiveness of Bladder Cancer Cells. (PMID:32517366)
• Silencing long non-coding RNA LINC00960 inhibits osteosarcoma proliferation by sponging miR-107 to downregulate SALL4. (PMID:35033873)
• LINC00960 regulates cell proliferation and glycolysis in pancreatic cancer through the miR-326-3p/TUFT1/AKT-mTOR axis. (PMID:36149758)
• lncRNA LINC00960 promotes apoptosis by sponging ubiquitin ligase Nrdp1-targeting miR-183-5p. (PMID:36722261)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.