LINC00989

Summary

LINC00989 (long intergenic non-protein coding RNA 989, HGNC:48918) is a long non-coding RNA gene on chromosome 4q21.21.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:48918
Approved symbol	LINC00989
Name	long intergenic non-protein coding RNA 989
Location	4q21.21
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000250334
Ensembl biotype	lncRNA
Entrez	100506035
RNAcentral	URS000075CD21 — lncRNA, 2054 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 46 — 46 lncRNA

ENST00000508174, ENST00000513155, ENST00000515544, ENST00000654276, ENST00000654687, ENST00000656371, ENST00000661529, ENST00000661950, ENST00000664228, ENST00000668018, ENST00000670961, ENST00000671684, ENST00000685595, ENST00000685699, ENST00000685909, ENST00000691929, ENST00000692563, ENST00000702315, ENST00000702341, ENST00000767419, ENST00000767420, ENST00000767421, ENST00000767422, ENST00000767423, ENST00000767424, ENST00000767425, ENST00000767426, ENST00000767427, ENST00000767428, ENST00000767429, ENST00000767430, ENST00000767431, ENST00000767432, ENST00000767433, ENST00000767434, ENST00000767435, ENST00000767436, ENST00000767437, ENST00000767438, ENST00000767439, ENST00000767440, ENST00000767441, ENST00000767442, ENST00000767443, ENST00000767444, ENST00000767445

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000508174 — 4 exons

Exon	Start	End
ENSE00002036801	79493152	79493585
ENSE00002045031	79513785	79513902
ENSE00002050191	79492407	79492623
ENSE00003858659	79575141	79576466

Expression profiles

Bgee: expression breadth ubiquitous, 128 present calls, max score 95.16.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.4735 / max 125.4594, expressed in 48 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
48499	0.2659	26
48500	0.2077	34

Top tissues by expression

128 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
monocyte	CL:0000576	95.16	gold quality
leukocyte	CL:0000738	93.99	gold quality
calcaneal tendon	UBERON:0003701	81.84	gold quality
subcutaneous adipose tissue	UBERON:0002190	81.43	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	79.89	gold quality
left coronary artery	UBERON:0001626	79.01	gold quality
adipose tissue	UBERON:0001013	78.82	gold quality
sural nerve	UBERON:0015488	78.10	gold quality
right coronary artery	UBERON:0001625	77.08	gold quality
blood	UBERON:0000178	76.09	gold quality
bone marrow cell	CL:0002092	76.03	gold quality
omental fat pad	UBERON:0010414	75.83	gold quality
tibial artery	UBERON:0007610	75.82	gold quality
popliteal artery	UBERON:0002250	75.81	gold quality
granulocyte	CL:0000094	74.84	gold quality
ectocervix	UBERON:0012249	74.41	gold quality
endocervix	UBERON:0000458	73.83	gold quality
uterine cervix	UBERON:0000002	73.48	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	71.92	gold quality
tibial nerve	UBERON:0001323	71.62	gold quality
thoracic mammary gland	UBERON:0005200	71.48	gold quality
gastrocnemius	UBERON:0001388	70.09	gold quality
muscle of leg	UBERON:0001383	69.55	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	69.33	gold quality
right atrium auricular region	UBERON:0006631	69.32	gold quality
skin of leg	UBERON:0001511	68.39	gold quality
lower esophagus muscularis layer	UBERON:0035833	67.99	gold quality
myometrium	UBERON:0001296	67.94	gold quality
lower esophagus	UBERON:0013473	67.94	gold quality
heart	UBERON:0000948	67.77	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	3.07

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.