LINC00992

Summary

LINC00992 (long intergenic non-protein coding RNA 992, HGNC:48943) is a long non-coding RNA gene on chromosome 5q23.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:48943
Approved symbol	LINC00992
Name	long intergenic non-protein coding RNA 992
Location	5q23.1
Locus type	RNA, long non-coding
Status	Approved
Aliases	GT3-INCP, ERINA
Ensembl gene	ENSG00000248663
Ensembl biotype	lncRNA
Entrez	728342
RNAcentral	URS000075B027 — lncRNA, 3091 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 12 — 12 lncRNA

ENST00000504107, ENST00000514186, ENST00000828611, ENST00000828612, ENST00000828613, ENST00000828614, ENST00000828615, ENST00000828616, ENST00000828617, ENST00000828618, ENST00000828619, ENST00000828620

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000504107 — 3 exons

Exon	Start	End
ENSE00002061219	117471902	117471938
ENSE00004241296	117454942	117455454
ENSE00004241299	117478981	117479372

Expression profiles

Bgee: expression breadth ubiquitous, 140 present calls, max score 86.63.

FANTOM5 (CAGE): breadth broad, TPM avg 2.0249 / max 47.5862, expressed in 310 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
58096	1.2423	143
58095	0.6913	285
58097	0.0912	70

Top tissues by expression

234 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
mucosa of transverse colon	UBERON:0004991	86.63	gold quality
rectum	UBERON:0001052	83.61	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	80.46	gold quality
body of pancreas	UBERON:0001150	79.64	gold quality
pancreas	UBERON:0001264	77.31	gold quality
islet of Langerhans	UBERON:0000006	76.97	gold quality
gall bladder	UBERON:0002110	75.61	gold quality
transverse colon	UBERON:0001157	73.45	gold quality
colonic mucosa	UBERON:0000317	72.74	gold quality
lower esophagus mucosa	UBERON:0035834	72.17	gold quality
mucosa of sigmoid colon	UBERON:0004993	70.23	gold quality
left lobe of thyroid gland	UBERON:0001120	70.13	gold quality
thyroid gland	UBERON:0002046	69.64	gold quality
ganglionic eminence	UBERON:0004023	69.41	gold quality
large intestine	UBERON:0000059	68.72	gold quality
right lobe of thyroid gland	UBERON:0001119	68.48	gold quality
palpebral conjunctiva	UBERON:0001812	68.46	gold quality
skin of leg	UBERON:0001511	68.40	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	68.34	gold quality
colon	UBERON:0001155	68.26	gold quality
right testis	UBERON:0004534	67.21	gold quality
esophagus mucosa	UBERON:0002469	67.09	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	67.09	gold quality
body of stomach	UBERON:0001161	66.96	gold quality
left testis	UBERON:0004533	66.91	gold quality
intestine	UBERON:0000160	66.66	gold quality
skin of abdomen	UBERON:0001416	66.44	gold quality
zone of skin	UBERON:0000014	66.05	gold quality
testis	UBERON:0000473	65.76	gold quality
stomach	UBERON:0000945	64.77	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.41

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 2)

• LINC00992 contributes to the oncogenic phenotypes in prostate cancer via targeting miR-3935 and augmenting GOLM1 expression. (PMID:32781986)
• LINC00992 exerts oncogenic activities in prostate cancer via regulation of SOX4. (PMID:34599930)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.