LINC00993

Summary

LINC00993 (long intergenic non-protein coding RNA 993, HGNC:48948) is a unprocessed pseudogene on chromosome 10p11.21.

At a glance

• Gene type: non-coding (transcribed_unprocessed_pseudogene) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:48948
Approved symbol	LINC00993
Name	long intergenic non-protein coding RNA 993
Location	10p11.21
Locus type	RNA, long non-coding
Status	Approved
Aliases	TCONS_l2_00002973
Ensembl gene	ENSG00000235687
Ensembl biotype	transcribed_unprocessed_pseudogene
Entrez	101929520
RNAcentral	URS000075E59E — lncRNA, 666 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 transcribed_unprocessed_pseudogene

ENST00000420453

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000420453 — 6 exons

Exon	Start	End
ENSE00001685927	37248118	37248240
ENSE00001727609	37261864	37261925
ENSE00001733563	37262483	37262539
ENSE00001737656	37264530	37264637
ENSE00001794605	37309097	37309180
ENSE00003812445	37315696	37315801

Expression profiles

Bgee: expression breadth ubiquitous, 118 present calls, max score 90.62.

Top tissues by expression

231 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
epithelium of mammary gland	UBERON:0003244	90.62	gold quality
mammary duct	UBERON:0001765	90.55	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	88.63	gold quality
mammary gland	UBERON:0001911	84.11	gold quality
thoracic mammary gland	UBERON:0005200	83.90	gold quality
left testis	UBERON:0004533	83.19	gold quality
right testis	UBERON:0004534	83.05	gold quality
testis	UBERON:0000473	78.90	gold quality
buccal mucosa cell	CL:0002336	76.18	gold quality
tibialis anterior	UBERON:0001385	72.44	silver quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	69.78	gold quality
pancreatic ductal cell	CL:0002079	68.82	silver quality
omental fat pad	UBERON:0010414	66.50	gold quality
peritoneum	UBERON:0002358	66.43	gold quality
adipose tissue of abdominal region	UBERON:0007808	65.40	gold quality
ileal mucosa	UBERON:0000331	64.61	gold quality
adipose tissue	UBERON:0001013	64.15	gold quality
subcutaneous adipose tissue	UBERON:0002190	63.79	gold quality
deltoid	UBERON:0001476	60.65	silver quality
epithelial cell of pancreas	CL:0000083	55.72	gold quality
cardiac muscle of right atrium	UBERON:0003379	54.34	gold quality
left ventricle myocardium	UBERON:0006566	54.23	gold quality
kidney epithelium	UBERON:0004819	53.93	gold quality
upper arm skin	UBERON:0004263	53.52	gold quality
upper leg skin	UBERON:0004262	53.10	silver quality
nipple	UBERON:0002030	52.61	gold quality
sperm	CL:0000019	51.57	gold quality
quadriceps femoris	UBERON:0001377	51.24	gold quality
oocyte	CL:0000023	50.29	gold quality
myocardium	UBERON:0002349	50.25	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	7.21

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• LncRNA TCONS_l2_00002973 correlates with less advanced tumor stage and favorable survival, and it also inhibits cancer cells proliferation while enhances apoptosis in triple-negative breast cancer. (PMID:31128002)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.