LINC01000

Summary

LINC01000 (long intergenic non-protein coding RNA 1000, HGNC:38541) is a long non-coding RNA gene on chromosome 7q32.1.

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:38541
Approved symbol	LINC01000
Name	long intergenic non-protein coding RNA 1000
Location	7q32.1
Locus type	RNA, long non-coding
Status	Approved
Aliases	FLJ45340
Entrez	402483
RNAcentral	URS000075B9E1 — lncRNA, 10263 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 0

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

None — 0 exons

Expression profiles

Top tissues by expression

0 total, by Bgee expression score (0-100, higher = more expressed):

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Protein identifiers

Canonical reviewed UniProt: None (reviewed: )

All UniProt accessions (0):

RefSeq proteins (0): (*=MANE)

Domains & families (InterPro)

Structure

Experimental structures (PDB)

0 structures.

Predicted structure (AlphaFold)

Function

Pathways and Gene Ontology

Reactome pathways

0 pathways

MSigDB gene sets: 0 (showing top):

GO Biological Process (0):

GO Molecular Function (0):

GO Cellular Component (0):

Protein interactions and networks

STRING

0 interactions, top by confidence (×1000):

IntAct

0 interactions, top by confidence:

SIGNOR signaling

0 interactions.

Disease & clinical

Clinical variants and AI predictions

ClinVar

0 variants total. Per-class counts are floors (≥ shown; pagination cap):

Classification	Count (floor)
Pathogenic	0
Likely pathogenic	0
Uncertain significance	0
Likely benign	0
Benign	0

Top pathogenic / likely-pathogenic (0)

SpliceAI

0 predictions. Top by Δscore:

AlphaMissense

0 scored. Top likely-pathogenic:

dbSNP variants (sampled 300 via entrez): RS1000034436 (7:128641801 T>C,G), RS1000275732 (7:128653736 G>A), RS1000341577 (7:128641527 G>A), RS1000409347 (7:128647204 C>A,T), RS1000795622 (7:128653833 C>A,T), RS1000898726 (7:128648992 C>T), RS1001122797 (7:128659812 G>A), RS1001278384 (7:128660097 C>T), RS1001353730 (7:128654733 C>G), RS1001443528 (7:128643263 A>C), RS1001452329 (7:128648587 A>G), RS1001679271 (7:128654601 C>T), RS1001897280 (7:128651002 A>G), RS1002066147 (7:128661436 C>A), RS1002438277 (7:128661095 T>A)

Disease associations

OMIM: gene `` | disease phenotypes:

GenCC curated gene-disease

Mondo (0):

Orphanet (0):

HPO phenotypes

0 total (0 of 0 shown, HPO-id order):

GWAS associations

0 associations (top):

Drugs & pharmacology

Drug and pharmacology data

Is drug target: no

PharmGKB: 0 entries

CTD chemical–gene interactions

21 total (human), top 21 by PubMed support.

Chemical	Actions (top 5)	PubMed papers
Particulate Matter	increases abundance, increases expression, decreases expression	2
bisphenol F	affects cotreatment, decreases expression	1
dicrotophos	increases expression	1
methylmercuric chloride	decreases expression	1
bisphenol A	affects cotreatment, decreases expression	1
butyraldehyde	decreases expression	1
pentanal	decreases expression	1
fipronil	affects cotreatment, decreases expression	1
bisphenol S	affects cotreatment, decreases expression	1
Air Pollutants	increases abundance, increases expression	1
Cisplatin	decreases expression	1
DEET	decreases expression, affects cotreatment	1
Dexamethasone	affects cotreatment, decreases expression	1
Indomethacin	affects cotreatment, decreases expression	1
Smoke	decreases expression	1
Thimerosal	increases expression	1
Valproic Acid	decreases expression	1
1-Methyl-3-isobutylxanthine	affects cotreatment, decreases expression	1
Antirheumatic Agents	decreases expression	1
Cadmium Chloride	increases expression	1
Lactic Acid	increases expression	1

Clinical trials (associated diseases)

0 trials via MONDO — disease-level, not drug-specific.