LINC01005

Summary

LINC01005 (long intergenic non-protein coding RNA 1005, HGNC:48963) is a long non-coding RNA gene on chromosome 7q11.21.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:48963
Approved symbol	LINC01005
Name	long intergenic non-protein coding RNA 1005
Location	7q11.21
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000228564
Ensembl biotype	lncRNA
Entrez	100506050
RNAcentral	URS000075A4F0 — lncRNA, 2911 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 57 — 57 lncRNA

ENST00000441691, ENST00000451440, ENST00000639687, ENST00000647881, ENST00000649157, ENST00000657780, ENST00000753136, ENST00000753137, ENST00000753138, ENST00000753139, ENST00000753140, ENST00000753141, ENST00000753142, ENST00000753143, ENST00000753144, ENST00000753145, ENST00000753146, ENST00000753147, ENST00000753148, ENST00000753149, ENST00000753150, ENST00000753151, ENST00000753152, ENST00000753153, ENST00000753154, ENST00000753729, ENST00000753730, ENST00000753731, ENST00000753732, ENST00000753733, ENST00000753734, ENST00000753735, ENST00000753736, ENST00000753737, ENST00000753738, ENST00000753739, ENST00000753740, ENST00000753741, ENST00000753742, ENST00000753743, ENST00000753744, ENST00000753745, ENST00000753746, ENST00000753747, ENST00000753748, ENST00000753749, ENST00000753750, ENST00000753751, ENST00000753895, ENST00000753896, ENST00000753897, ENST00000753898, ENST00000753899, ENST00000753900, ENST00000753901, ENST00000753902, ENST00000753903

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000441691 — 3 exons

Exon	Start	End
ENSE00001401167	64027852	64027912
ENSE00001716047	64028516	64028774
ENSE00001804572	64028191	64028410

Expression profiles

Bgee: expression breadth broad, 78 present calls, max score 85.38.

Top tissues by expression

78 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	85.38	gold quality
right testis	UBERON:0004534	84.08	gold quality
left testis	UBERON:0004533	83.93	gold quality
testis	UBERON:0000473	83.36	gold quality
ventricular zone	UBERON:0003053	59.64	silver quality
monocyte	CL:0000576	56.64	gold quality
duodenum	UBERON:0002114	56.06	gold quality
prefrontal cortex	UBERON:0000451	54.26	gold quality
liver	UBERON:0002107	53.73	silver quality
multicellular organism	UBERON:0000468	53.37	gold quality
islet of Langerhans	UBERON:0000006	52.40	gold quality
right lobe of thyroid gland	UBERON:0001119	51.78	gold quality
blood	UBERON:0000178	51.69	gold quality
lymph node	UBERON:0000029	51.67	gold quality
superior frontal gyrus	UBERON:0002661	51.26	gold quality
gastrocnemius	UBERON:0001388	51.01	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	49.82	silver quality
fundus of stomach	UBERON:0001160	47.44	gold quality
small intestine	UBERON:0002108	46.03	gold quality
putamen	UBERON:0001874	44.99	gold quality
Brodmann (1909) area 9	UBERON:0013540	44.59	silver quality
tibial artery	UBERON:0007610	44.45	gold quality
body of pancreas	UBERON:0001150	44.24	gold quality
right adrenal gland cortex	UBERON:0035827	43.88	silver quality
right lobe of liver	UBERON:0001114	43.78	silver quality
ovary	UBERON:0000992	43.68	gold quality
skin of abdomen	UBERON:0001416	43.66	silver quality
substantia nigra	UBERON:0002038	43.32	gold quality
right ovary	UBERON:0002118	43.25	silver quality
frontal cortex	UBERON:0001870	43.20	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.61

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Exosomal LINC01005 derived from oxidized low-density lipoprotein-treated endothelial cells regulates vascular smooth muscle cell phenotypic switch. (PMID:32663367)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.