LINC01010

Summary

LINC01010 (long intergenic non-protein coding RNA 1010, HGNC:48978) is a long non-coding RNA gene on chromosome 6q23.2.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:48978
Approved symbol	LINC01010
Name	long intergenic non-protein coding RNA 1010
Location	6q23.2
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000236700
Ensembl biotype	lncRNA
Entrez	154092
RNAcentral	URS0000759A88 — lncRNA, 1717 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 68 — 68 lncRNA

ENST00000431422, ENST00000440090, ENST00000456749, ENST00000653261, ENST00000655247, ENST00000655975, ENST00000656596, ENST00000656789, ENST00000658387, ENST00000659389, ENST00000660399, ENST00000661139, ENST00000664108, ENST00000666623, ENST00000667755, ENST00000669104, ENST00000669308, ENST00000702277, ENST00000702565, ENST00000742847, ENST00000742848, ENST00000742849, ENST00000742850, ENST00000742851, ENST00000742852, ENST00000742853, ENST00000742854, ENST00000742855, ENST00000792709, ENST00000792710, ENST00000792711, ENST00000792712, ENST00000792713, ENST00000792714, ENST00000792715, ENST00000792716, ENST00000792717, ENST00000792718, ENST00000792719, ENST00000792720, ENST00000792721, ENST00000792722, ENST00000792723, ENST00000792724, ENST00000792725, ENST00000792726, ENST00000792727, ENST00000792728, ENST00000792729, ENST00000792730, ENST00000792731, ENST00000792732, ENST00000792733, ENST00000792734, ENST00000792735, ENST00000792736, ENST00000792737, ENST00000792738, ENST00000792739, ENST00000792740, ENST00000792741, ENST00000792742, ENST00000792743, ENST00000792744, ENST00000792745, ENST00000792746, ENST00000792747, ENST00000792748

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000431422 — 4 exons

Exon	Start	End
ENSE00001612330	134502788	134504581
ENSE00001742666	134437315	134437881
ENSE00001792677	134464741	134464849
ENSE00003865080	134343307	134343359

Expression profiles

Bgee: expression breadth ubiquitous, 117 present calls, max score 79.70.

FANTOM5 (CAGE): breadth broad, TPM avg 3.6527 / max 326.2450, expressed in 221 samples.

FANTOM5 promoters (5 alternative TSS)

Promoter ID	TPM avg	Samples expressed
69894	2.5738	180
69893	0.9339	160
69885	0.1261	12
69896	0.0095	3
69892	0.0093	7

Top tissues by expression

210 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
sperm	CL:0000019	79.70	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	79.21	gold quality
left testis	UBERON:0004533	73.07	gold quality
right testis	UBERON:0004534	70.79	gold quality
testis	UBERON:0000473	70.60	gold quality
bone marrow cell	CL:0002092	62.16	silver quality
right lobe of liver	UBERON:0001114	61.88	gold quality
superficial temporal artery	UBERON:0001614	60.33	gold quality
cortical plate	UBERON:0005343	59.60	silver quality
ventricular zone	UBERON:0003053	58.18	silver quality
adult organism	UBERON:0007023	56.96	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	56.73	silver quality
hindlimb stylopod muscle	UBERON:0004252	56.73	silver quality
prefrontal cortex	UBERON:0000451	56.50	gold quality
esophagus squamous epithelium	UBERON:0006920	55.89	gold quality
gingival epithelium	UBERON:0001949	55.48	gold quality
liver	UBERON:0002107	55.17	gold quality
putamen	UBERON:0001874	54.40	gold quality
left coronary artery	UBERON:0001626	53.64	gold quality
amygdala	UBERON:0001876	53.63	gold quality
gall bladder	UBERON:0002110	52.56	gold quality
ectocervix	UBERON:0012249	52.46	gold quality
amniotic fluid	UBERON:0000173	52.34	gold quality
Brodmann (1909) area 9	UBERON:0013540	52.31	gold quality
endometrium	UBERON:0001295	51.39	gold quality
substantia nigra	UBERON:0002038	51.16	gold quality
caudate nucleus	UBERON:0001873	51.04	gold quality
gingiva	UBERON:0001828	51.03	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	50.66	gold quality
lymph node	UBERON:0000029	50.34	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.92

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 2)

• HBV HBx-Downregulated lncRNA LINC01010 Attenuates Cell Proliferation by Interacting with Vimentin. (PMID:34830378)
• Non-coding RNA LINC01010 regulates macrophage polarization and innate immune functions by modulating NFkappaB signaling pathway. (PMID:38403999)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.