LINC01012

Summary

LINC01012 (long intergenic non-protein coding RNA 1012, HGNC:48986) is a long non-coding RNA gene on chromosome 6p22.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:48986
Approved symbol	LINC01012
Name	long intergenic non-protein coding RNA 1012
Location	6p22.1
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000281706
Ensembl biotype	lncRNA
Entrez	100507173
RNAcentral	URS000075BAE5 — lncRNA, 2785 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 78 — 78 lncRNA

ENST00000625477, ENST00000628328, ENST00000628762, ENST00000629732, ENST00000662411, ENST00000685096, ENST00000686567, ENST00000687474, ENST00000687535, ENST00000687781, ENST00000687799, ENST00000688605, ENST00000689802, ENST00000692784, ENST00000692987, ENST00000693575, ENST00000693645, ENST00000702246, ENST00000783746, ENST00000783747, ENST00000783748, ENST00000783749, ENST00000783750, ENST00000783751, ENST00000783752, ENST00000783753, ENST00000783754, ENST00000783755, ENST00000783756, ENST00000783757, ENST00000783758, ENST00000783759, ENST00000783760, ENST00000783761, ENST00000783762, ENST00000783763, ENST00000783764, ENST00000783765, ENST00000783766, ENST00000783767, ENST00000783768, ENST00000783769, ENST00000783770, ENST00000783771, ENST00000783772, ENST00000783773, ENST00000783774, ENST00000783775, ENST00000783776, ENST00000783777, ENST00000783778, ENST00000783779, ENST00000783780, ENST00000783781, ENST00000783782, ENST00000783783, ENST00000783784, ENST00000783785, ENST00000783786, ENST00000783787, ENST00000783788, ENST00000783789, ENST00000783790, ENST00000783791, ENST00000783792, ENST00000783793, ENST00000783794, ENST00000783795, ENST00000783796, ENST00000783797, ENST00000783798, ENST00000783799, ENST00000783800, ENST00000783801, ENST00000783802, ENST00000783803, ENST00000783804, ENST00000783805

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000625477 — 2 exons

Exon	Start	End
ENSE00004158075	27693796	27694506
ENSE00004158147	27702314	27702867

Expression profiles

Bgee: expression breadth ubiquitous, 150 present calls, max score 76.35.

FANTOM5 (CAGE): breadth broad, TPM avg 1.3272 / max 43.0608, expressed in 621 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
66573	1.0231	548
66574	0.2321	108
66575	0.0720	25

Top tissues by expression

239 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
cortical plate	UBERON:0005343	76.35	gold quality
ganglionic eminence	UBERON:0004023	74.21	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	74.11	gold quality
cerebellar hemisphere	UBERON:0002245	73.74	gold quality
cerebellar cortex	UBERON:0002129	73.61	gold quality
right hemisphere of cerebellum	UBERON:0014890	72.81	gold quality
ventricular zone	UBERON:0003053	72.65	gold quality
left ovary	UBERON:0002119	71.62	gold quality
cerebellum	UBERON:0002037	71.31	gold quality
mucosa of transverse colon	UBERON:0004991	70.71	gold quality
body of pancreas	UBERON:0001150	70.49	gold quality
right ovary	UBERON:0002118	68.97	gold quality
rectum	UBERON:0001052	68.01	gold quality
lower esophagus mucosa	UBERON:0035834	67.72	gold quality
granulocyte	CL:0000094	67.57	gold quality
pancreas	UBERON:0001264	66.49	gold quality
ovary	UBERON:0000992	66.45	gold quality
lymph node	UBERON:0000029	64.94	gold quality
left lobe of thyroid gland	UBERON:0001120	63.49	gold quality
bone marrow cell	CL:0002092	63.38	silver quality
colonic epithelium	UBERON:0000397	63.16	silver quality
transverse colon	UBERON:0001157	62.70	gold quality
thyroid gland	UBERON:0002046	62.63	gold quality
small intestine Peyer’s patch	UBERON:0003454	62.41	gold quality
vermiform appendix	UBERON:0001154	62.17	gold quality
right lobe of thyroid gland	UBERON:0001119	61.96	gold quality
spleen	UBERON:0002106	61.84	gold quality
prefrontal cortex	UBERON:0000451	61.12	gold quality
islet of Langerhans	UBERON:0000006	61.04	gold quality
small intestine	UBERON:0002108	60.99	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	4.83

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.