LINC01018

Summary

LINC01018 (long intergenic non-protein coding RNA 1018, HGNC:27394) is a long non-coding RNA gene on chromosome 5p15.31.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:27394
Approved symbol	LINC01018
Name	long intergenic non-protein coding RNA 1018
Location	5p15.31
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000250056
Ensembl biotype	lncRNA
OMIM	616385
Entrez	255167
RNAcentral	URS000075E197 — lncRNA, 3053 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 44 — 44 lncRNA

ENST00000505626, ENST00000507582, ENST00000507628, ENST00000513844, ENST00000652158, ENST00000657872, ENST00000658539, ENST00000658850, ENST00000659049, ENST00000659245, ENST00000659556, ENST00000659719, ENST00000660957, ENST00000661215, ENST00000664093, ENST00000665924, ENST00000666121, ENST00000667172, ENST00000667226, ENST00000668899, ENST00000669289, ENST00000671065, ENST00000674529, ENST00000674813, ENST00000674954, ENST00000675055, ENST00000675222, ENST00000675337, ENST00000675394, ENST00000675676, ENST00000675715, ENST00000675993, ENST00000676036, ENST00000676406, ENST00000752507, ENST00000752508, ENST00000752509, ENST00000752510, ENST00000752511, ENST00000752512, ENST00000752513, ENST00000752514, ENST00000752515, ENST00000752516

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000505626 — 5 exons

Exon	Start	End
ENSE00002032808	6583603	6583801
ENSE00002042215	6585774	6586027
ENSE00002064423	6582420	6582601
ENSE00004098696	6582135	6582266
ENSE00004098710	6586228	6589234

Expression profiles

Bgee: expression breadth ubiquitous, 156 present calls, max score 92.44.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.1930 / max 16.3622, expressed in 88 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
55631	0.1546	72
55630	0.0384	21

Top tissues by expression

240 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
right lobe of liver	UBERON:0001114	92.44	gold quality
liver	UBERON:0002107	88.77	gold quality
left ovary	UBERON:0002119	79.74	gold quality
prefrontal cortex	UBERON:0000451	78.34	gold quality
islet of Langerhans	UBERON:0000006	77.55	gold quality
ventricular zone	UBERON:0003053	76.41	gold quality
right ovary	UBERON:0002118	76.19	gold quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	75.60	gold quality
Brodmann (1909) area 9	UBERON:0013540	75.21	gold quality
ovary	UBERON:0000992	75.16	gold quality
cortical plate	UBERON:0005343	74.17	gold quality
anterior cingulate cortex	UBERON:0009835	74.03	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	72.90	gold quality
frontal cortex	UBERON:0001870	72.09	gold quality
right frontal lobe	UBERON:0002810	72.04	gold quality
neocortex	UBERON:0001950	72.00	gold quality
adenohypophysis	UBERON:0002196	71.87	gold quality
ganglionic eminence	UBERON:0004023	71.75	gold quality
hindlimb stylopod muscle	UBERON:0004252	71.13	gold quality
pituitary gland	UBERON:0000007	70.54	gold quality
apex of heart	UBERON:0002098	69.70	gold quality
cerebellar hemisphere	UBERON:0002245	69.70	gold quality
cerebellar cortex	UBERON:0002129	69.65	gold quality
sperm	CL:0000019	69.38	gold quality
right atrium auricular region	UBERON:0006631	69.27	gold quality
right hemisphere of cerebellum	UBERON:0014890	69.24	gold quality
heart left ventricle	UBERON:0002084	68.74	gold quality
pancreas	UBERON:0001264	68.68	gold quality
cardiac atrium	UBERON:0002081	68.65	gold quality
hypothalamus	UBERON:0001898	68.60	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.62

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 2)

• LINC01018 and SMIM25 sponged miR-182-5p in endometriosis revealed by the ceRNA network construction. (PMID:33237828)
• Long non-coding RNA LINC01018 inhibits human glioma cell proliferation and metastasis by directly targeting miRNA-182-5p. (PMID:36094613)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.