LINC01048

Summary

LINC01048 (long intergenic non-protein coding RNA 1048, HGNC:49042) is a long non-coding RNA gene on chromosome 13q13.3.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:49042
Approved symbol	LINC01048
Name	long intergenic non-protein coding RNA 1048
Location	13q13.3
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000230390
Ensembl biotype	lncRNA
Entrez	103695431
RNAcentral	URS00007E4388 — lncRNA, 541 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000414480, ENST00000827904

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000414480 — 4 exons

Exon	Start	End
ENSE00001668863	37484470	37484545
ENSE00001703959	37484285	37484393
ENSE00004240291	37484705	37484785
ENSE00004240293	37481464	37481727

Expression profiles

Bgee: expression breadth broad, 63 present calls, max score 89.38.

Top tissues by expression

63 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	89.38	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	61.35	gold quality
placenta	UBERON:0001987	56.58	gold quality
monocyte	CL:0000576	54.26	gold quality
myometrium	UBERON:0001296	53.46	gold quality
vermiform appendix	UBERON:0001154	53.22	gold quality
olfactory segment of nasal mucosa	UBERON:0005386	52.70	gold quality
blood	UBERON:0000178	52.45	gold quality
gastrocnemius	UBERON:0001388	52.15	gold quality
subcutaneous adipose tissue	UBERON:0002190	51.74	gold quality
heart left ventricle	UBERON:0002084	50.30	gold quality
adipose tissue	UBERON:0001013	50.21	gold quality
descending thoracic aorta	UBERON:0002345	50.12	gold quality
heart	UBERON:0000948	49.45	gold quality
thoracic mammary gland	UBERON:0005200	49.23	gold quality
tibial artery	UBERON:0007610	47.90	gold quality
adult mammalian kidney	UBERON:0000082	47.88	silver quality
left coronary artery	UBERON:0001626	47.39	gold quality
right atrium auricular region	UBERON:0006631	47.32	gold quality
Ammon’s horn	UBERON:0001954	46.89	gold quality
multicellular organism	UBERON:0000468	46.76	gold quality
smooth muscle tissue	UBERON:0001135	46.62	gold quality
endometrium	UBERON:0001295	46.26	gold quality
omental fat pad	UBERON:0010414	46.17	gold quality
body of pancreas	UBERON:0001150	46.03	silver quality
thoracic aorta	UBERON:0001515	45.67	gold quality
muscle layer of sigmoid colon	UBERON:0035805	45.40	gold quality
testis	UBERON:0000473	45.38	gold quality
ascending aorta	UBERON:0001496	45.30	gold quality
left testis	UBERON:0004533	44.92	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.30

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• LINC01048 was expressed higher in the cutaneous squamous cell carcinoma (CSCC) tissues and recurrence tissues compared with that in adjacent normal tissues and non-recurrence tissues. Kaplan-Meier analysis revealed the negative correlation between LINC01048 expression and the overall survival and disease-free survival of CSCC patients. (PMID:30931936)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.