LINC01053

Summary

LINC01053 (long intergenic non-protein coding RNA 1053, HGNC:49047) is a long non-coding RNA gene on chromosome 13q12.13.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:49047
Approved symbol	LINC01053
Name	long intergenic non-protein coding RNA 1053
Location	13q12.13
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000238169
Ensembl biotype	lncRNA
Entrez	102723318
RNAcentral	URS000075EC5F — lncRNA, 1777 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 4 — 4 lncRNA

ENST00000457628, ENST00000656176, ENST00000803583, ENST00000803584

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000457628 — 3 exons

Exon	Start	End
ENSE00001617015	25181399	25181533
ENSE00001627404	25186524	25186699
ENSE00001672394	25189259	25190643

Expression profiles

Bgee: expression breadth broad, 36 present calls, max score 87.27.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.2902 / max 153.9752, expressed in 19 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
134459	0.1543	10
134460	0.0984	8
134458	0.0376	6

Top tissues by expression

36 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	87.27	gold quality
tibial artery	UBERON:0007610	56.59	gold quality
heart left ventricle	UBERON:0002084	52.12	gold quality
prefrontal cortex	UBERON:0000451	51.40	gold quality
adult mammalian kidney	UBERON:0000082	49.99	silver quality
blood	UBERON:0000178	49.54	silver quality
monocyte	CL:0000576	48.79	silver quality
frontal cortex	UBERON:0001870	45.85	gold quality
cerebellum	UBERON:0002037	45.10	silver quality
cerebellar cortex	UBERON:0002129	44.94	silver quality
cerebellar hemisphere	UBERON:0002245	44.88	silver quality
urinary bladder	UBERON:0001255	44.84	silver quality
vermiform appendix	UBERON:0001154	44.23	silver quality
skin of leg	UBERON:0001511	43.88	silver quality
right hemisphere of cerebellum	UBERON:0014890	43.62	silver quality
vagina	UBERON:0000996	43.14	gold quality
spleen	UBERON:0002106	43.06	silver quality
Brodmann (1909) area 9	UBERON:0013540	43.01	silver quality
cerebral cortex	UBERON:0000956	42.43	silver quality
putamen	UBERON:0001874	42.36	gold quality
nucleus accumbens	UBERON:0001882	42.24	gold quality
dorsolateral prefrontal cortex	UBERON:0009834	41.69	silver quality
anterior cingulate cortex	UBERON:0009835	40.62	silver quality
amygdala	UBERON:0001876	40.57	gold quality
caudate nucleus	UBERON:0001873	40.06	silver quality
substantia nigra	UBERON:0002038	40.04	silver quality
right frontal lobe	UBERON:0002810	39.29	silver quality
Ammon’s horn	UBERON:0001954	38.95	silver quality
C1 segment of cervical spinal cord	UBERON:0006469	38.04	silver quality
hypothalamus	UBERON:0001898	37.92	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	1.80

Regulation

Is transcription factor: no

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.