LINC01061

Summary

LINC01061 (long intergenic non-protein coding RNA 1061, HGNC:49084) is a long non-coding RNA gene on chromosome 4q26.

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:49084
Approved symbol	LINC01061
Name	long intergenic non-protein coding RNA 1061
Location	4q26
Locus type	RNA, long non-coding
Status	Approved
Aliases	FLJ14186, KIKAT
Entrez	401149
RNAcentral	URS000075E55C — lncRNA, 4818 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 0

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

None — 0 exons

Expression profiles

Top tissues by expression

0 total, by Bgee expression score (0-100, higher = more expressed):

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 4)

• LINC01061 sponges miR-612 to increase SEMA4D expression. (PMID:30967271)
• Enhanced LINC01061 Levels as a Serum Biomarker in Gastric Cancer and Promotion of Malignant Transformation. (PMID:33910210)
• Long non-coding RNA KIKAT/LINC01061 as a novel epigenetic regulator that relocates KDM4A on chromatin and modulates viral reactivation. (PMID:34111227)
• LINC01061 triggers inflammation and inflammasome activation in autoimmune thyroiditis via microRNA-612/BRD4 axis. (PMID:35998503)

Cross-species orthologs

0 orthologs

Protein

Protein identifiers

Canonical reviewed UniProt: None (reviewed: )

All UniProt accessions (0):

RefSeq proteins (0): (*=MANE)

Domains & families (InterPro)

Structure

Experimental structures (PDB)

0 structures.

Predicted structure (AlphaFold)

Function

Pathways and Gene Ontology

Reactome pathways

0 pathways

MSigDB gene sets: 0 (showing top):

GO Biological Process (0):

GO Molecular Function (0):

GO Cellular Component (0):

Protein interactions and networks

STRING

0 interactions, top by confidence (×1000):

IntAct

0 interactions, top by confidence:

SIGNOR signaling

0 interactions.

Disease & clinical

Clinical variants and AI predictions

ClinVar

0 variants total. Per-class counts are floors (≥ shown; pagination cap):

Classification	Count (floor)
Pathogenic	0
Likely pathogenic	0
Uncertain significance	0
Likely benign	0
Benign	0

Top pathogenic / likely-pathogenic (0)

SpliceAI

0 predictions. Top by Δscore:

AlphaMissense

0 scored. Top likely-pathogenic:

dbSNP variants (sampled 300 via entrez): RS1000878007 (4:119408031 A>G), RS1001531071 (4:119405782 G>A), RS1001539558 (4:119410442 C>T), RS1001639601 (4:119410241 G>A), RS1001900702 (4:119405167 C>G,T), RS10019309 (4:119405930 C>G,T), RS10019421 (4:119406043 C>A,G,T), RS1002027348 (4:119405609 A>T), RS1002266584 (4:119405046 TCTC>T), RS10023107 (4:119407514 G>T), RS1002542320 (4:119411655 G>A), RS1002678218 (4:119411478 GTA>G), RS1002940913 (4:119406862 G>C), RS10031129 (4:119406046 T>A,C,G), RS10034691 (4:119407571 T>C,G)

Disease associations

OMIM: gene `` | disease phenotypes:

GenCC curated gene-disease

Mondo (0):

Orphanet (0):

HPO phenotypes

0 total (0 of 0 shown, HPO-id order):

GWAS associations

0 associations (top):

Drugs & pharmacology

Drug and pharmacology data

Is drug target: no

PharmGKB: 0 entries

CTD chemical–gene interactions

5 total (human), top 5 by PubMed support.

Chemical	Actions (top 5)	PubMed papers
dicrotophos	increases expression	1
butyraldehyde	decreases expression	1
fipronil	decreases expression, affects cotreatment	1
DEET	affects cotreatment, decreases expression	1
Lactic Acid	increases expression	1

Clinical trials (associated diseases)

0 trials via MONDO — disease-level, not drug-specific.