LINC01063

Summary

LINC01063 (long intergenic non-protein coding RNA 1063, HGNC:49092) is a long non-coding RNA gene on chromosome 3q29.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:49092
Approved symbol	LINC01063
Name	long intergenic non-protein coding RNA 1063
Location	3q29
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000232065
Ensembl biotype	lncRNA
Entrez	101929769
RNAcentral	URS00008E3A05 — lncRNA, 342 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 2 — 2 lncRNA

ENST00000441644, ENST00000827417

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000441644 — 2 exons

Exon	Start	End
ENSE00001749780	196632388	196632700
ENSE00004239275	196631009	196631645

Expression profiles

Bgee: expression breadth ubiquitous, 128 present calls, max score 94.78.

FANTOM5 (CAGE): breadth broad, TPM avg 0.7810 / max 14.7425, expressed in 440 samples.

FANTOM5 promoters (2 alternative TSS)

Promoter ID	TPM avg	Samples expressed
46373	0.7171	398
46374	0.0640	18

Top tissues by expression

128 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	94.78	gold quality
monocyte	CL:0000576	79.62	gold quality
leukocyte	CL:0000738	78.76	gold quality
bone marrow cell	CL:0002092	73.42	gold quality
sural nerve	UBERON:0015488	73.18	gold quality
cortical plate	UBERON:0005343	72.19	gold quality
ganglionic eminence	UBERON:0004023	71.18	gold quality
nucleus accumbens	UBERON:0001882	70.73	gold quality
substantia nigra	UBERON:0002038	70.23	gold quality
granulocyte	CL:0000094	69.52	gold quality
colonic epithelium	UBERON:0000397	69.09	gold quality
hindlimb stylopod muscle	UBERON:0004252	68.86	gold quality
caudate nucleus	UBERON:0001873	68.74	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	68.56	gold quality
putamen	UBERON:0001874	68.48	gold quality
amygdala	UBERON:0001876	68.21	gold quality
temporal lobe	UBERON:0001871	68.18	gold quality
Ammon’s horn	UBERON:0001954	67.35	gold quality
hypothalamus	UBERON:0001898	66.65	gold quality
gall bladder	UBERON:0002110	66.36	gold quality
superior frontal gyrus	UBERON:0002661	66.34	gold quality
mucosa of transverse colon	UBERON:0004991	66.33	gold quality
esophagogastric junction muscularis propria	UBERON:0035841	66.22	gold quality
anterior cingulate cortex	UBERON:0009835	66.16	gold quality
lower esophagus	UBERON:0013473	65.38	gold quality
lower esophagus muscularis layer	UBERON:0035833	65.38	gold quality
brain	UBERON:0000955	65.37	gold quality
Brodmann (1909) area 9	UBERON:0013540	64.98	gold quality
cerebral cortex	UBERON:0000956	64.93	gold quality
prefrontal cortex	UBERON:0000451	64.84	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	0.76

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• LINC01063 functions as an oncogene in melanoma through regulation of miR-5194-mediated SOX12 expression. (PMID:35256570)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.