LINC01082

Summary

LINC01082 (long intergenic non-protein coding RNA 1082, HGNC:49125) is a long non-coding RNA gene on chromosome 16q24.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:49125
Approved symbol	LINC01082
Name	long intergenic non-protein coding RNA 1082
Location	16q24.1
Locus type	RNA, long non-coding
Status	Approved
Aliases	TCONS_00024492
Ensembl gene	ENSG00000269186
Ensembl biotype	lncRNA
OMIM	614978
Entrez	100506542
RNAcentral	URS000075C5C7 — lncRNA, 456 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 12 — 12 lncRNA

ENST00000601250, ENST00000650200, ENST00000654153, ENST00000669926, ENST00000806578, ENST00000806579, ENST00000806580, ENST00000806581, ENST00000806582, ENST00000806583, ENST00000806584, ENST00000806585

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000601250 — 2 exons

Exon	Start	End
ENSE00003133662	86196181	86196412
ENSE00003150637	86199512	86199720

Expression profiles

Bgee: expression breadth ubiquitous, 115 present calls, max score 93.35.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.3299 / max 76.5046, expressed in 49 samples.

FANTOM5 promoters (3 alternative TSS)

Promoter ID	TPM avg	Samples expressed
155437	0.1882	32
155439	0.0770	26
155438	0.0648	22

Top tissues by expression

215 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	93.35	gold quality
mucosa of transverse colon	UBERON:0004991	87.27	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	87.19	gold quality
rectum	UBERON:0001052	87.16	gold quality
right testis	UBERON:0004534	86.32	gold quality
colonic epithelium	UBERON:0000397	84.68	gold quality
urinary bladder	UBERON:0001255	84.07	gold quality
left testis	UBERON:0004533	83.99	gold quality
muscle layer of sigmoid colon	UBERON:0035805	81.81	gold quality
testis	UBERON:0000473	81.08	gold quality
buccal mucosa cell	CL:0002336	80.78	gold quality
large intestine	UBERON:0000059	78.91	gold quality
colon	UBERON:0001155	78.86	gold quality
sural nerve	UBERON:0015488	78.80	silver quality
esophagogastric junction muscularis propria	UBERON:0035841	78.24	gold quality
intestine	UBERON:0000160	78.10	gold quality
transverse colon	UBERON:0001157	78.04	gold quality
lower esophagus mucosa	UBERON:0035834	77.93	gold quality
mucosa of sigmoid colon	UBERON:0004993	77.20	gold quality
lower esophagus muscularis layer	UBERON:0035833	77.01	gold quality
lower esophagus	UBERON:0013473	77.00	gold quality
prostate gland	UBERON:0002367	76.28	gold quality
colonic mucosa	UBERON:0000317	75.65	gold quality
small intestine Peyer’s patch	UBERON:0003454	75.42	gold quality
stomach	UBERON:0000945	75.29	gold quality
cardiac muscle of right atrium	UBERON:0003379	75.02	gold quality
left ventricle myocardium	UBERON:0006566	75.02	gold quality
fundus of stomach	UBERON:0001160	74.85	gold quality
small intestine	UBERON:0002108	74.85	gold quality
body of stomach	UBERON:0001161	74.77	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	2.26

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 2)

• LINC01082 may act in suppressing the incidence and development of colon cancer via suppressing cell proliferation, migration and invasion. (PMID:31432387)
• LINC01082 Inhibits Non-Small Cell Lung Cancer by Targeting the miR-543/TNRC6A Axis. (PMID:36719626)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.