LINC01085

Summary

LINC01085 (long intergenic non-protein coding RNA 1085, HGNC:27198) is a long non-coding RNA gene on chromosome 4p15.33.

At a glance

• Gene type: non-coding (transcribed_processed_pseudogene) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:27198
Approved symbol	LINC01085
Name	long intergenic non-protein coding RNA 1085
Location	4p15.33
Locus type	RNA, long non-coding
Status	Approved
Ensembl gene	ENSG00000248698
Ensembl biotype	transcribed_processed_pseudogene
Entrez	152742
RNAcentral	URS000075B913 — lncRNA, 1998 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 transcribed_processed_pseudogene

ENST00000511195

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000511195 — 1 exons

Exon	Start	End
ENSE00002043544	14126339	14126664

Expression profiles

Bgee: expression breadth ubiquitous, 116 present calls, max score 87.59.

FANTOM5 (CAGE): breadth tissue_specific, TPM avg 0.4787 / max 59.9443, expressed in 136 samples.

FANTOM5 promoters (4 alternative TSS)

Promoter ID	TPM avg	Samples expressed
46952	0.2573	83
46953	0.1184	43
46950	0.0633	25
46951	0.0397	18

Top tissues by expression

238 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	87.59	silver quality
buccal mucosa cell	CL:0002336	78.44	silver quality
stromal cell of endometrium	CL:0002255	74.69	gold quality
lower lobe of lung	UBERON:0008949	58.58	silver quality
pancreatic ductal cell	CL:0002079	58.08	silver quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	56.83	silver quality
pigmented layer of retina	UBERON:0001782	56.65	gold quality
nucleus accumbens	UBERON:0001882	54.47	gold quality
epithelial cell of pancreas	CL:0000083	54.42	gold quality
cardiac muscle of right atrium	UBERON:0003379	54.34	gold quality
left ventricle myocardium	UBERON:0006566	54.23	gold quality
seminal vesicle	UBERON:0000998	53.99	gold quality
kidney epithelium	UBERON:0004819	53.93	gold quality
upper arm skin	UBERON:0004263	53.52	gold quality
monocyte	CL:0000576	52.67	gold quality
caudate nucleus	UBERON:0001873	51.72	gold quality
right adrenal gland cortex	UBERON:0035827	51.61	gold quality
metanephros cortex	UBERON:0010533	51.58	gold quality
cortex of kidney	UBERON:0001225	51.51	gold quality
endometrium	UBERON:0001295	51.39	gold quality
leukocyte	CL:0000738	51.16	gold quality
putamen	UBERON:0001874	51.06	gold quality
tibialis anterior	UBERON:0001385	50.96	silver quality
myocardium	UBERON:0002349	50.25	gold quality
prefrontal cortex	UBERON:0000451	49.95	gold quality
metanephros	UBERON:0000081	49.38	gold quality
anterior cingulate cortex	UBERON:0009835	49.27	gold quality
C1 segment of cervical spinal cord	UBERON:0006469	48.94	gold quality
Brodmann (1909) area 9	UBERON:0013540	48.61	gold quality
deltoid	UBERON:0001476	48.13	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	4.06

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• Results found significant increased expression of LOC15274 in patients with pulmonary tuberculosis compared with uninfected groups indicating that LOC152742 may potentially act as a novel biomarker for diagnosis of active tuberculosis. (PMID:30790332)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.