LINC01087

Summary

LINC01087 (long intergenic non-protein coding RNA 1087, HGNC:49144) is a long non-coding RNA gene on chromosome 2q21.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:49144
Approved symbol	LINC01087
Name	long intergenic non-protein coding RNA 1087
Location	2q21.1
Locus type	RNA, long non-coding
Status	Approved
Aliases	ERLC1
Ensembl gene	ENSG00000224559
Ensembl biotype	lncRNA
Entrez	101927994
RNAcentral	URS00001A2CE1 — lncRNA, 3516 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 1 — 1 lncRNA

ENST00000431979

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000431979 — 2 exons

Exon	Start	End
ENSE00001608232	131637025	131639178
ENSE00001791991	131648254	131649615

Expression profiles

Bgee: expression breadth broad, 62 present calls, max score 84.46.

Top tissues by expression

175 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	84.46	gold quality
primordial germ cell in gonad	CL:0000670 ∩ UBERON:0000991	74.24	gold quality
left testis	UBERON:0004533	71.30	gold quality
right testis	UBERON:0004534	71.28	gold quality
testis	UBERON:0000473	70.01	gold quality
sural nerve	UBERON:0015488	64.99	silver quality
lower lobe of lung	UBERON:0008949	57.08	silver quality
prostate gland	UBERON:0002367	56.12	gold quality
stromal cell of endometrium	CL:0002255	51.81	silver quality
upper lobe of lung	UBERON:0008948	49.97	silver quality
monocyte	CL:0000576	49.75	silver quality
cortex of kidney	UBERON:0001225	47.84	gold quality
right frontal lobe	UBERON:0002810	47.71	gold quality
islet of Langerhans	UBERON:0000006	46.49	silver quality
body of pancreas	UBERON:0001150	45.25	silver quality
muscle of leg	UBERON:0001383	45.25	gold quality
pancreas	UBERON:0001264	45.01	silver quality
anatomical system	UBERON:0000467	44.97	gold quality
multicellular organism	UBERON:0000468	44.70	gold quality
gastrocnemius	UBERON:0001388	44.69	gold quality
material anatomical entity	UBERON:0000465	44.67	gold quality
lung	UBERON:0002048	44.26	silver quality
right adrenal gland cortex	UBERON:0035827	44.20	silver quality
right atrium auricular region	UBERON:0006631	43.91	silver quality
cardiac atrium	UBERON:0002081	43.65	silver quality
skeletal muscle tissue of rectus abdominis	UBERON:0004511	43.37	gold quality
oviduct epithelium	UBERON:0004804	42.68	gold quality
secondary oocyte	CL:0000655	42.57	gold quality
thoracic mammary gland	UBERON:0005200	42.51	gold quality
right coronary artery	UBERON:0001625	42.49	silver quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 1.

Experiment	Marker?	Max mean expression
E-ANND-3	yes	3.11

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 2)

• The abundance of the long intergenic non-coding RNA 01087 differentiates between luminal and triple-negative breast cancers and predicts patient outcome. (PMID:33068730)
• LINC01087 indicates a poor prognosis of glioma patients with preoperative MRI. (PMID:34817752)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.