LINC01117

Summary

LINC01117 (long intergenic non-protein coding RNA 1117, HGNC:49260) is a long non-coding RNA gene on chromosome 2q31.1.

At a glance

• Gene type: non-coding (lncRNA) — no protein product; not a drug target. Variant/disease associations are omitted (they would be positional, from an overlapping protein-coding gene).

Identifiers

Gene identifiers

Field	Value
HGNC ID	HGNC:49260
Approved symbol	LINC01117
Name	long intergenic non-protein coding RNA 1117
Location	2q31.1
Locus type	RNA, long non-coding
Status	Approved
Aliases	uc.109
Ensembl gene	ENSG00000224577
Ensembl biotype	lncRNA
Entrez	102724224
RNAcentral	URS000075E811 — lncRNA, 656 nt, 1 organism(s)

Gene structure

Transcript identifiers

Ensembl transcripts: 42 — 42 lncRNA

ENST00000443670, ENST00000652227, ENST00000652995, ENST00000702503, ENST00000702732, ENST00000814385, ENST00000814386, ENST00000814387, ENST00000814388, ENST00000814389, ENST00000814390, ENST00000814391, ENST00000814392, ENST00000814393, ENST00000814394, ENST00000814395, ENST00000814396, ENST00000814397, ENST00000814398, ENST00000814399, ENST00000814400, ENST00000814401, ENST00000814402, ENST00000814403, ENST00000814404, ENST00000814405, ENST00000814406, ENST00000814407, ENST00000814408, ENST00000814409, ENST00000814410, ENST00000814411, ENST00000814412, ENST00000814413, ENST00000814414, ENST00000814415, ENST00000814416, ENST00000814417, ENST00000814418, ENST00000814419, ENST00000814420, ENST00000814421

RefSeq mRNA: 0 — MANE Select: None

Canonical transcript exons

ENST00000443670 — 4 exons

Exon	Start	End
ENSE00001626143	176637710	176638007
ENSE00001717778	176655464	176655520
ENSE00001742789	176655698	176655958
ENSE00001762270	176639491	176639573

Expression profiles

Bgee: expression breadth ubiquitous, 121 present calls, max score 83.06.

FANTOM5 (CAGE): breadth broad, TPM avg 0.7105 / max 22.1598, expressed in 414 samples.

FANTOM5 promoters (1 alternative TSS)

Promoter ID	TPM avg	Samples expressed
23882	0.7105	414

Top tissues by expression

121 total, by Bgee expression score (0-100, higher = more expressed):

Tissue	Anatomy ID	Expression score	Quality
male germ line stem cell (sensu Vertebrata) in testis	CL:0000089 ∩ UBERON:0000473	83.06	gold quality
sural nerve	UBERON:0015488	74.62	gold quality
calcaneal tendon	UBERON:0003701	74.51	gold quality
esophagus mucosa	UBERON:0002469	70.66	gold quality
lower esophagus mucosa	UBERON:0035834	69.13	gold quality
nucleus accumbens	UBERON:0001882	67.73	gold quality
subcutaneous adipose tissue	UBERON:0002190	67.67	gold quality
metanephros cortex	UBERON:0010533	67.07	gold quality
body of uterus	UBERON:0009853	66.15	gold quality
thoracic mammary gland	UBERON:0005200	65.81	gold quality
myometrium	UBERON:0001296	65.73	gold quality
spleen	UBERON:0002106	65.63	gold quality
adult mammalian kidney	UBERON:0000082	64.99	gold quality
mucosa of stomach	UBERON:0001199	64.93	gold quality
skin of abdomen	UBERON:0001416	64.92	gold quality
fallopian tube	UBERON:0003889	64.70	gold quality
adipose tissue	UBERON:0001013	64.61	gold quality
left adrenal gland cortex	UBERON:0035825	64.57	gold quality
esophagus	UBERON:0001043	64.51	gold quality
left uterine tube	UBERON:0001303	64.44	gold quality
tibial nerve	UBERON:0001323	64.08	gold quality
cortex of kidney	UBERON:0001225	64.03	gold quality
right ovary	UBERON:0002118	63.97	gold quality
kidney	UBERON:0002113	63.71	gold quality
smooth muscle tissue	UBERON:0001135	63.63	gold quality
zone of skin	UBERON:0000014	63.47	gold quality
left adrenal gland	UBERON:0001234	63.23	gold quality
left ovary	UBERON:0002119	63.23	gold quality
ovary	UBERON:0000992	63.22	gold quality
right uterine tube	UBERON:0001302	62.84	gold quality

Single-cell (SCXA)

Detected in 1 experiment(s), a significant marker in 0.

Experiment	Marker?	Max mean expression
E-ANND-3	no	3.28

Regulation

Is transcription factor: no

Literature-anchored findings (GeneRIF, showing 1)

• LINC01117 inhibits invasion and migration of lung adenocarcinoma through influencing EMT process. (PMID:37384755)

Cross-species orthologs

0 orthologs

Protein

Non-coding RNA — no protein product; not a drug target.

Function

No curated pathway, Gene-Ontology, or interaction data.

Disease & clinical

No curated disease, variant, or cancer-driver associations.

Drugs & pharmacology

No drug or pharmacology data — not an established drug target.